Buffalo Bulls vs Central Michigan Chippewas Prediction, Odds and Picks for Today, 11/12/25

The Buffalo Bulls hit the road for Mount Pleasant to battle the Central Michigan Chippewas at Kelly/Shorts Stadium, and the winner will secure bowl eligibility. The Bulls are 4-1 in the conference, just a half-game behind Western Michigan, who won Tuesday, for first place. The Bulls rolled Bowling Green 28-3 last time out on Nov. 1, cashing as a 3-point underdog, but they’re still 1-5-1 ATS in the past seven games. On the road, Buffalo is a dismal 1-2 ATS in three games in the conference, too. The Bulls have a rather mediocre offense, going for 24.8 PPG, while the defense has been the key to their success, allowing just 19.6 ppg.

The Chips lost at Western Michigan against their biggest rivalry, covering as a 6-point underdog in a 24-21 setback. Central Michigan has racked up three consecutive covers, while going 5-1 ATS in the past six contests. While Buffalo has won three of the past four meetings in this series, and 3-1 ATS in that span, Central won the most recent meeting at home, 31-27 on Nov. 9, 2022 as a 1-point favorite. Central Michigan is on fire lately, and cashing well against the number. If this game were in Buffalo, it might end differently, but venue matters. Back the home side.

Buffalo vs Central Michigan prediction: Central Michigan -1 (-110) available at time of publishing. Playable to -2.5.

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