College Football Parlays

Get our best College Football parlays every week of the 2025-26 season. Our experts combine their best CFB bets to create the best NCAAF parlay picks this week. You can also find our College Football same game parlays all season long.

Read More
Friday's college football parlay
Tomorrow
Charlotte 49ers
South Florida Bulls
Charlotte @ South Florida · Point Spread
Charlotte +27.0
Our Analysis

The Charlotte 49ers hit the road to take on the South Florida Bulls at Raymond James Stadium in Tampa in the second American Conference battle for the Niners. USF opens its league schedule with this Friday night game. Charlotte suffered a 28-17 loss at Jerry Richardson Stadium against Rice on Sept. 18, and it is 0-3 SU/ATS against FBS opponents this season, with just a win over FCS Monmouth (NJ) as its lone bright spot. And, even then, the 49ers barely won that game 42-35 in a shootout at home. The defense for Charlotte is rather shoddy, as it has allowed 28 or more points in 3 of 4 games. Its best effort was a 20-3 loss against Bill Belichick’s struggling North Carolina side on Sept. 6.

For South Florida, it was ranked for a hot minute after topping Boise State and Florida in the first 2 games, both as underdogs. However, USF was drilled 49-12 at Miami on Sept. 13, tumbling from the rankings. It rebounded last week with a 63-14 tune-up over FCS South Carolina State at home, but there are still plenty of questions. The defense has looked good outside of the Canes debacle, while the offense has been so-so. QB Byrum Brown is a solid dual-threat option, but he struggled against Florida and Miami a bit. He should find plenty of open spaces to do his thing about the 49ers, but the Bulls laying 4 touchdowns seems a bit much. Take Charlotte and the points, and hope its offense can give us something.

Charlotte vs USF prediction: Charlotte 49ers +27 (-110) available at time of publishing. Playable to +26.

Bet like a Caesar with this AMAZING new customer offer from Caesars Sportsbook. If you bet just $1, you’ll receive DOUBLE YOUR WINNINGS on your next 20 bets! Become a Caesars member 👥 using the Caesars promo code PWCONTENT20X, where you can bet on our Charlotte vs USF picks.

Sam Houston State Bearkats
New Mexico State Aggies
Sam Houston State @ New Mexico State · Game Totals
Over 53.0
Our Analysis

The winless Sam Houston State Bearkats hit the road to take on the New Mexico State Aggies in a Conference USA tilt on Thursday at 9 pm ET on CBS Sports Network. It’s the standalone game in college football that night, too. I don’t know how many people are excited about this game outside of a small sliver of Texas and extreme southern New Mexico, but I am fired up for this game. And, hopefully the scoreboard operator at Aggie Memorial Stadium in Las Cruces limbers up, because he/she is going to be extremely busy on Thursday night, as are any cheerleaders doing push-ups for each score.

Sam Houston has allowed at least 37 points in all 4 of its games to date, while scoring at least 20 points in 3 of those outings. It was dusted 55-0 at Texas on Sept. 20, but that’s the only game it didn’t get to at least 20 points. On the road, it is averaging 22.0 PPG while allowing 39.0 PPG. Oh, and the Bearkats are 0-4 against the spread (ATS), too, if you’re a same-game parlay (SGP) bettor.

The Aggies topped FCS Bryant and Tulsa earlier this season, while losing by at least 18 points in the past 2 road games at Louisiana Tech and rival New Mexico. The Aggies have allowed 43.5 PPG in the past 2 games, and it has scored at least 19 points in 3 of 4 games, cashing the over in the past 2. Both of these teams, desperate for a win, are going to take full advantage of a lack of resistance from the other. Expect a ton of points in this Thursday game in the Land of Enchantment.

Sam Houston vs New Mexico State prediction: Over 53 (-110) available at time of publishing. Playable to 56.5.

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $200 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ Sam Houston vs New Mexico State predictions.

West Virginia Mountaineers
BYU Cougars
West Virginia @ BYU · Point Spread
BYU -19.0
Our Analysis

We head to Provo on Friday night for a Big 12 matchup between the West Virginia Mountaineers and the BYU Cougars. Both teams are on a quick turnaround after playing on Saturday, with the added wrinkle that the Mountaineers have to cross the continent. West Virginia is struggling at 2-3 in the first year of Rich Rodriguez’s (second) tenure, and this is pretty much a rebuild in every sense of the word. For BYU, things are going great at 4-0, but they are looking at a really tough Big 12 schedule after this one. I do not love their outlook for long term success this season, but I do think the smartest play on Friday is to take the far better team, especially playing at home on a short week. Give me BYU to cover -19.

One of the reasons for BYU’s success has been freshmen QB Bear Bachmeier. After booting their starting QB over the summer, there wasn’t a lot of hope in Provo. But then Bachmeier turned out to be a star, as he can beat you on the ground or in the air. He is fun, if you haven’t watched him yet. Surrounding him is a Cougar team that is just tough and physical. They are not fun to play against. They should also be way better than West Virginia at this point. The Mountaineers lost their starting QB to a foot injury, and it is unclear when or if he will return. The problem, aside from just having a backup QB in there in general, is that this West Virginia offense wants to be a dynamic rushing attack, but that is much harder to do when defenses do not have to respect the threat of a passing attack. That is where the Mountaineers are right now. I expect them to struggle to score all night, and eventually BYU should pull away.

West Virginia vs BYU prediction: BYU Cougars -19 (-110) available at time of publishing. Playable to -20.

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $200 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ West Virginia vs BYU predictions.

BET +581 NOW WITH
Andrew Wilsher Managing Editor of Pickswise
Andrew Wilsher

What Is A College Football Parlay

A college football parlay bet is when you combine multiple selections into a single bet, with all of the selections needing to win to cash your ticket. While the difficulty of winning a college football parlay increases with the number of selections you add, so do the odds. To calculate the odds of a parlay you multiply the odds of each selection so the more selections, the bigger the parlay odds. You can also use our Parlay Calulator to do all the math for you!

College football parlay bets are great options for bettors who prefer to wager smaller amounts on bigger odds. Most spreads and totals markets will have odds of around -110 or -120, a three-team parlay on these markets typically pays around 6/1 (+600) with a four-team parlay paying around 12/1 (+1200) Check out the typical odds of your ATS parlays below.

Our experts will highlight the best college football picks this week to combine into a college football parlay, offering you even more variation into how you want to bet on this week’s college football action.

NCAAF Picks and Parlays

With so many games played on any given weekend our NCAAF Picks and Parlays are incredibly popular and its easy to see why. You can combine a multitude of markets into an NCAAF Parlay and that’s what our experts do right here, every weekend. We combine some of our top NCAAF Picks and NCAAF Predictions to make our weekly NCAAF Parlay. Check back on Friday each week to find our best NCAAF Picks and Parlays for the upcoming round of games.

How To Win A College Football Parlay

College football parlay bets despite their popularity can be one of the most difficult bets to hit with increased difficulty with each selection you add to your parlay.

College Football differs from the pro ranks with its scheduling and there is far less parity throughout the regular season. With this, you see in some cases no money line offered, and spreads as high as -40. This presents a unique type of challenge, particularly when adding multiple selections so here are three quick tips to better your chances of winning long-term with your college football parlays.

  1. Keep to either a 2, 3, or 4 team parlay – Any more than this will be tough to keep profitable long term, despite the increased parlay odds. 
  2. Shop the odds – Online sportsbooks compete to offer the best odds, and while there may only be a marginal difference on each selection, it adds up in a college football parlay., If you can wager three picks at +100 each instead of -125, your payout would be $800.00 instead of $583.20 to a $100 stake.
  3. Managing your bankroll – it’s obvious, and not unique to NCAAF parlays, and should be considered all the time, but being disciplined with your bankroll is key long term. Not all parlays will win, that’s part of sports betting, but if you keep your stake consistent, at odds of around 6/1, you only need to win 1 in 7 parlays to break even, any better than that is profit.

College Football Parlay Odds Chart and Payouts

You can parlay just about any combination of straight wagers, as long as they’re not correlated or from the same game. But typically bettors will parlay either picks against the spread or on the totals. You will usually get around -110 odds for each individual selection on these markets, but be sure to shop around as different sportsbooks will have more juice added to the odds than others. You can of course parlay money line odds, or odds that aren’t -110 and for these you should use our Parlay Calulator for an accurate payout calculation. But the average payouts for traditional college football parlays are as seen below.

Parlay Odds Chart
Parlay SizePaid Odds$100 Stake Payout
2+264$362.00
3+595$695.00
4+1228$1,328.00
5+2435$2,535.00
6+4741$4,841.00
7+9142$9,242.00
8+17544$17,644.00
9+33585$33,685.00
10+64208$64,308.00

How To Bet On College Football Picks And Parlays

Betting on college football picks and parlays is a quick and easy process with any of the best online sportsbooks. To create a parlay, simply add multiple selections to your bet slip and click the parlay option before entering your desired stake amount and placing your bet.

Due to the popularity of parlay betting, pay a considerable amount of attention to these markets, and in shopping around you can find great variations in the odds, and lines, and bonuses such as price boosts or parlay insurance. 

Pickswise
*
By signing up you agree to our terms and privacy policy