49ers vs Colts Anytime Touchdown Scorer Predictions for MNF Week 16

Indianapolis Colts tight end Tyler Warren (84) celebrates with tight end Mo Alie-Cox (81) and tight end Drew Ogletree (85) after a touchdown during the second half against the Houston Texans at Lucas Oil Stadium.
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44-year-old Philip Rivers will make his home debut off the couch for the Colts against a surging 49ers team, winners of 4 straight and still alive for the #1 seed in the NFC. Let’s dive into our 49ers vs Colts anytime TD scorer best bets for MNF. You can also find out our NFL picks for every game throughout the season — including pro NFL bettor Chris Farley’s 49ers vs Colts MNF best bets as he looks to add to his current 14-4 run!

49ers vs Colts anytime touchdown scorer best bet: George Kittle (+125)

Odds available at DraftKings Sportsbook at time of publishing

A healthy George Kittle is good for football. After missing 5 of the first 6 weeks of the season, Kittle has put together 8 straight games of 4+ receptions, while finding the end zone 5 times. Christian McCaffrey overshadows Kittle in the passing game, but Kittle’s 26.5% target share since Week 10 is an indication that Brock Purdy has no problem throwing the ball in Kittle’s direction, especially against a lackluster Colts passing defense.

After 2 winners on Saturday night at +650 and +407 odds, don’t miss our 49ers vs Colts parlay picks for MNF tonight!

49ers vs Colts anytime touchdown scorer pick: Tyler Warren (+280)

Odds available at BetMGM at time of publishing.

Let’s back the other tight end star in 49ers vs Colts for our 2nd TD scorer prediction. Tyler Warren was off to a strong start to the season, but his play has declined in recent weeks. Philip Rivers is most definitely not the answer for Warren to have success on MNF, but the Colts use him in a variety of ways, especially down in the red zone. If the Colts find themselves in a 4th and short inside the 5-yard line, look for Warren to tush-push his way in or have Rivers find him over the top of the defense.

Don’t miss Prop Holliday’s best MNF player prop bets for 49ers vs Colts, targeting Jonathan Taylor and Tyler Warren

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