Best MLB player prop bets for today 5/22: Phillies and Rockies bats start off hot

Philadelphia Phillies third baseman Alec Bohm (28) reacts with second baseman Bryson Stott (5) after hitting a two run home run against the Tampa Bay Rays in the second inning at George M. Steinbrenner Field.
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We’ve got a 9-game MLB slate on tap today, which begins at 12:35 pm ET with Rangers vs Yankees, although there are some early weather concerns on the East Coast. As a result, I recommend being extremely cautious in your betting approach. I’m turning my attention to Denver where we could see plenty of early runs. Let’s dive into my best MLB prop bets for Thursday, May 22, while you can also find out our MLB picks for every matchup today.

Best MLB prop bet: Phillies/Rockies F5 over 5.5 runs (-120)

Odds available at DraftKings Sportsbook at time of publishing.

Facing an elite offense is one thing, but facing that same offense twice in the first half of the season is another. German Marquez opened his 2025 campaign shutting down the Phillies offense through 6 innings pitched. Since then, it’s been tough sledding for the veteran. His xERA and xBA rank in the bottom 26th and 13th percentile. To make matters worse, this game is in Coors Field, where the Phillies have erupted for 25 runs through 3 games.

On the other side of the diamond, Ranger Suarez will be making his 3rd start of the year after an IL stint. Rather than taking the Phillies’ individual side of over 3.5 runs through 5 innings, we’ll bank on the Rockies finding a couple of runs versus the lefty.

Find out our expert’s Phillies vs Rockies best bet for today — we’re 29-19 this season!

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