The 2026 NFL playoffs continue on Sunday and the action gets started with a crunch matchup in the AFC as the Buffalo Bills lock horns with the Jacksonville Jaguars. Josh Allen and the Bills will see this as a great opportunity to finally reach the Super Bowl with the Chiefs and Ravens out of contention, but in their way stands an upstart Jaguars team that has been on a serious roll after winning its last 8 games of the season. With this game essentially a pick’em, it should be one heck of a matchup. And to add to the drama, I’ve pieced together a Bills vs Jaguars parlay at +900 odds with bet365. Let’s dive in, while you can also find out our NFL picks for EVERY playoff matchup after our experts finished the season up +78.1 units!
Bills ML (-110)
Under 51.5 (-110)
Travis Etienne to score a touchdown (-145)
Bills vs Jaguars parlay odds: +900
If you’re looking to bet on our Bills vs Jags parlay, we recommend using bet365. Not only will you find the best odds, but new users can click here to sign up now and receive $200 in bonus bets INSTANTLY when they make their first $5 wager.
Buffalo Bills ML over Jacksonville Jaguars (-110)
It’s the momentum Bills fans have been waiting years for. FINALLY, Patrick Mahomes and the Chiefs will not stand in their way of postseason success. However, Allen and company didn’t fully capitalize, as they could only muster a Wild Card spot after conceding the AFC East to the Patriots, and must now go on the road throughout if they want to reach the Super Bowl. They should at least get off to a winning start at the expense of the Jaguars. The Jags have been excellent in Liam Coen’s first year as head coach, particularly behind an excellent pass defense that allowed the 3rd-fewest passing yards per attempt and secured 22 interceptions.
However, what the Bills have to their advantage is experience. Sean McDermott’s team have been a mainstay in the postseason and that should give them the edge against a very young Jags team that could find the occasion too much for them. While Buffalo has been disappointing by their standards, they have won 5 of their last 6 games and earned a particularly eyecatching win over the Patriots on the road last month. The Bills’ offense ranks 3rd in passing yards per attempt and 2nd in yards per carry, so can beat you in multiple ways. This one could go down to the wire, but I can’t see past Buffalo advancing to the Divisional Round.
Read our full Bills vs Jaguars predictions for Sunday’s Wild Card game — expert Chris Farley is on a 5-1 run!
Under 51.5 (-110)
As mentioned, the Jags’ defense has been the key to their success this season, and I believe it should do enough to keep the total below this lofty number. Jacksonville has not allowed more than 20 points in any of its last 6 games, and given how solid this D has been against the pass, I’m expecting them to do all they can to frustrate Allen and stymie his impact.
As for the Bills’ D, they have allowed the 4th-fewest passing yards per attempt and 6th-fewest passing touchdowns, so should have some success in slowing down Trevor Lawrence. The big question is on the Buffalo run defense, which allowed 5.1 yards per carry during the regular season and gave up the most rushing touchdowns in the NFL. However, Travis Etienne has been inconsistent this year, going over 50 rushing yards in his last 4 games, so he could be slowed down. There should be points in this one, but I’m not expecting a shootout.
Travis Etienne to score a touchdown (-145)
While it is true that Etienne has been ineffecient on the ground, I still like him to find the end zone on Sunday. While there’s every chance he could take advantage of the Bills’ turnstile run D, having scored 7 TDs on the ground, Etienne has also been formidable through the air, catching 6 touchdown passes. He has 6 TDs in his last 5 games and should be used regularly to try to penetrate the Buffalo defense. Coen will also likely lean on his run game as a means of keeping the clock moving and keeping Allen off the field. Given this is -145 odds, it gives our Bills vs Jags SGP a massive boost due to it being a contrarian leg, and I’m happy to roll the dice with it.
Click here to add us to your Google preferred sources and never miss a story
