The 2025 NFL season is here with the headline-driving Dallas Cowboys heading to Philadelphia for a ring ceremony! The Eagles are currently 7.5-point favorites in their home opener as the defending Super Bowl champions and the total sits at an advantageous 47.5. It will be interesting to see how the Eagles shake off last year’s win and refocus on the daunting task of repeating, while we see how the Cowboys look without All-Pro EDGE Micah Parsons since he was traded to Green Bay for a pair of first-round picks and DT Kenny Clark.
I’ll be writing all season long for Pickswise, managing the Thursday Night Football spot, and you can expect a wide variety of bets from me in terms of markets, player props and angles. Everything will come with a unit size attached so if you’re skeptical of some of the longer odds I play, just make sure you’re adjusting your unit size to match! Let’s dive in, while you can also find out all of our expert NFL picks for EVERY GAME in Week 1 and throughout the season!
Read our full Cowboys vs Eagles prediction for TNF
Cowboys vs Eagles Same Game Parlay: Saquon Barkley under 96.5 rushing yards + Anytime Touchdown Scorer (+290) 0.75u
Odds available at bet365 at time of publishing.
The 2024 NFL Offensive Player of the year is coming off well over 450 touches (482) when you factor in the postseason, and that’s not a number they’ll want him near again if the Eagles want to repeat. If the spread tells us anything, a 7.5 line in a divisional game to kick off the year is pretty big. Backup RB Will Shipley and new addition AJ Dillon should have a role early in the season to keep the miles off Barkley.
I like the under by itself if you can get 94.5 or higher, but getting this at nearly 3-1 on bet365 with the TD is too good to pass up. Other books are at +220 with his yards at 90.5/92.5, so I like the value here. If you can’t get this on bet365, just pivot to 1 unit on under 95.5 on DK or 94.5 on Fanatics Sportsbook, but nothing lower than 94.5. This is a reverse-correlation play that jumps the odds as we are betting on Barkley going under (negative) while scoring a TD (positive). It’s not as far-fetched as you would assume and it really ties into the game script along with managing Barkley’s workload earlier in the season.
Check out JutPicks’ Cowboys vs Eagles anytime touchdown scorer best bets, inc. a longshot at +800 odds!
Cowboys vs Eagles player prop bet: Jahan Dotson 30+ Receiving Yards (+550) 0.65u
Cowboys vs Eagles player prop bet: Jahan Dotson 40+ Receiving Yards (+1100) 0.35u
Odds available at bet365 at time of publishing.
If you do not have access to Bet365 based on your state, you can still get Dotson alt-lines on Fanduel’s new feature “Your Way”. Dotson is the clear-cut WR3 and now has a full offseason in this Philadelphia offense after being traded just before the 2024 season. I’ll buy a bit of camp hype on Dotson, who’s been praised for learning more of the route tree and building a rapport with Jalen Hurts this offseason.
If Dallas loads up to stop Saquon, as we all assume they will, Philly should be able to make them pay with a deep shot to Dotson. He had catches last season of 27, 27, 36, and 19; if you exclude the last game of the season where they rested starters, he’s in the 3-4 target range. I can see that slightly upticking to 4-6 this season, and if that is the case, this line is wrong. 1u across the alt-line mini ladder. If you’re skeptical of the alt-lines, I still like his over 7.5 receiving yards for 1u, which is widely available.
Now lock in our Cowboys vs Eagles Same Game Parlay picks for TNF at +669 odds