College Football Week 11 Betting Guide: CFB Expert picks for Saturday, November 8

Sep 13, 2025; Tuscaloosa, Alabama, USA; Alabama wide receiver Ryan Williams (2), Alabama wide receiver Rico Scott (11) and Alabama tight end Kaleb Edwards (81) celebrate a touchdown by Williams against Wisconsin at Saban Field at Bryant-Denny Stadium.
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College football Saturday has arrived! We have another huge lineup of CFB games to sink our teeth into on Saturday, November 8, across all the Power conferences and Group of 5 conferences. We have tons of mega matchups to look forward to, including unbeaten Texas A&M making the trip to Missouri, along with LSU battling Alabama and Indiana visiting Penn State. Pickswise’s expert CFB handicappers have been hot this season, so let’s see if we can keep that up here! You can find out all of our NCAAF picks and CFB predictions for more than 30 games on Saturday, plus we have our college football expert’s best bets of the day, along with our parlays and Same Game Parlay picks to help you bet better across all of the action. Let’s dive in!

College football Saturday best bets for Week 11

College football Week 11 parlays

Go for the big payday on Saturday with our handicappers’ best CFB parlays for the day:

  • College football Saturday parlaydon’t miss our expert’s 3-leg parlay at +740 odds!
  • Indiana vs Penn State Same Game Parlay — after cashing our NBA SGP on Thursday night, let’s see if we can do the same for this crunch Big Ten matchup

College football Week 11 picks

Below, you’ll find our betting previews and NCAAF predictions for all the biggest games in Week 11. However, you can also check out our expert CFB picks for more than 30 of Saturday’s matchups!

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