And before you know it, the final week of the college football regular season is upon us. We go into rivalry week with much still to be decided when it comes to bowl eligibility and the College Football Playoff, which is exactly the way we like it as fans.
For the final time in the 2025 regular season, it’s time to take an early look at the lines and odds for the biggest games in the upcoming Week 14 slate, courtesy of DraftKings, before capping it off with my favorite bet from the bunch. Vanderbilt cruised to a cover for us last week, improving the early-week best bet record to 8-4. Let’s find another winner this week, not only from this column, but from the rest of our NCAA predictions, as well.
CFB Week 14 Early Lines and Odds
- Western Michigan -7 (-108) @ Eastern Michigan – Tuesday, November 25
- Memphis -5.5 (-108) vs. Navy – Thursday, November 27
- Ole Miss -7 (-115) @ Mississippi State – Friday, November 28
- Utah -13.5 (-110) @ Kansas – Friday, November 28
- Iowa -5.5 (-112) @ Nebraska – Friday, November 28
- Ohio -6 (-112) @ Buffalo – Friday, November 28
- Georgia -13.5 (-110) vs. Georgia Tech – Friday, November 28
- North Texas -19.5 (-115) vs. Temple – Friday, November 28
- San Diego State -1.5 (-110) @ New Mexico – Friday, November 28
- Boise State -3 (-115) @ Utah State – Friday, November 28
- Texas A&M -2.5 (-108) @ Texas – Friday, November 28
- Indiana -28.5 (-105) @ Purdue – Friday, November 28
- Arizona -1.5 (-105) @ Arizona State – Friday, November 28
- Ohio State -10.5 (-108) @ Michigan – Saturday, November 29
- Miami -7 (-108) @ Pitt – Saturday, November 29
- South Carolina -2.5 (-108) vs. Clemson – Saturday, November 29
- Texas Tech -21 (-110) @ West Virginia – Saturday, November 29
- Louisville -3.5 (-108) vs. Kentucky – Saturday, November 29
- Baylor -3 (-108) vs. Houston – Saturday, November 29
- Miami (OH) -17.5 (-115) vs. Ball State – Saturday, November 29
- East Carolina -6.5 (-110) @ Florida Atlantic – Saturday, November 29
- Toledo -10.5 (-108) @ Central Michigan – Saturday, November 29
- BYU -17.5 (-108) vs. UCF – Saturday, November 29
- Western Kentucky -2.5 (-110) @ Jacksonville State – Saturday, November 29
- Oregon -6.5 (-112) @ Washington – Saturday, November 29
- Oklahoma -10 (-108) vs. LSU – Saturday, November 29
- Tennessee -3 (-105) vs. Vanderbilt – Saturday, November 29
- Missouri -2.5 (-112) @ Arkansas – Saturday, November 29
- TCU -4 (-110) vs. Cincinnati – Saturday, November 29
- James Madison -22.5 (-108) @ Coastal Carolina – Saturday, November 29
- Florida -2.5 (-115) vs. Florida State – Saturday, November 29
- Virginia -10.5 (-110) vs. Virginia Tech – Saturday, November 29
- Alabama -5.5 (-112) @ Auburn – Saturday, November 29
- NC State -7.5 (-108) vs. North Carolina – Saturday, November 29
- USC -20.5 (-110) vs. UCLA – Saturday, November 29
- Illinois -7 (-105) vs. Northwestern – Saturday, November 29
- SMU -12.5 (-110) @ California – Saturday, November 29
- UNLV -7.5 (-112) @ Nevada – Saturday, November 29
- Notre Dame -32.5 (-110) @ Stanford – Saturday, November 29
- Fresno State -2.5 (-115) @ San Jose State – Saturday, November 29
- Hawaii -10 (-112) vs. Wyoming – Saturday, November 29
CFB Week 14 Early Best Bet: Oklahoma Sooners -10 over LSU Tigers (-108)
Oklahoma and LSU come into this game on very different trajectories. The Sooners are on the doorstep of the College Football Playoff, while the Tigers are coachless and probably ready for the season to be over. At least that’s what I took from their 13-10 win over Western Kentucky last week, a game in which the Tigers failed to surpass 330 total yards or run for at least 4 yards per carry against a bad Conference USA defense. The performance was a microcosm of the season for the Bayou Bengals, who are bowl eligible at 7-4 — but that wasn’t the goal coming into the year. The goal was to make the CFP and win a national title.
On the other side, Oklahoma has absolutely everything to play for. There was no hangover for the Sooners after beating Tennessee and Alabama in consecutive games, as they held Missouri to 301 total yards, 3-for-15 on third downs and just 2 yards per rush. Sitting at 9-2, the Sooners figure to remain squarely in the top-9 of the CFP rankings this week, but they cannot afford another loss if they want a chance to play for the national championship.
Simply put, I don’t have much confidence in LSU’s ability to score enough in this game to cover, much less win — especially without QB Garrett Nussmeier. The Tigers have been a shell of themselves offensively of late, and nothing is going to come easy against an Oklahoma defense that surrenders just 14 points (sixth nationally) and 280.5 yards per game (11th), in addition to yielding 4.3 yards per play (6th) and allowing only 40% of opposing red-zone trips to end in a touchdown (sixth). More recently, LSU has been one of the worst offenses in the country as it pertains to PPA per play, success rate and havoc allowed outside of garbage time since Week 9 — which is a scary thought considering Oklahoma is top 50 in defensive PPA per play and success rate in that span despite facing some of the best offenses in the country like Ole Miss, Tennessee and Alabama. Furthermore, the Sooners are top 10 in total havoc generated since the end of October. It’s OU all the way for me in this one.
Click here to add us to your Google preferred sources and never miss a story
