Copa America Predictions & Quarterfinal Best Bets for Saturday, July 6 - Feat. Colombia vs Panama and Uruguay vs Brazil

Brazil forward Rodrygo (10) reacts after scoring a goal against the United States in the first half during the Continental Clasico at Camping World Stadium.
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Ian Wilkerson


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Journalist since 1994, having previously working at BBC Sport before joining the Racing Post in 2006. A specialist in football and golf betting. A keen runner who presents the top-10 weekly running podcast, The Long Run. For Ian Wilkerson media enquiries, please email
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We will reach the conclusion of the 2024 Copa America quarterfinals by the end of Saturday, July 6, with all 4 semifinalists known. The final 2 matchups will take place on Saturday evening, starting with Colombia vs Panama live at 6:00 pm ET on FS1. That will be immediately followed on the same station by a huge clash between soccer giants Uruguay and Brazil at 9:00 pm ET. We’ll have our expert soccer predictions throughout Copa America as well as EVERY Euro 2024 game, but for now, let’s dive into our 2024 Copa America best bets for Thursday.

Colombia vs Panama best bet: Colombia ML & Over 2.5 goals (+100)

Colombia will be delighted with the way they have progressed through the group stage at the 2024 Copa America and they should be confident about securing a semifinal place at Panama’s expense. The South American nation can be satisfied with the 1-1 draw they posted with Brazil to ensure they came out on top of Group D following victories over Paraguay and Costa Rica, and they have managed to extend their unbeaten run to 26 matches.

They will have to cope without the suspended Jefferson Lerma for Saturday’s game against Panama, but that should not be too difficult against a team that finished runners-up in their section and only beat USA 2-1 despite the USMNT playing 70 minutes with 10 men. That result for Panama came after they were well beaten 3-1 by Marcelo Bielsa’s Uruguay in their opening game, which does not bode well for a strong performance against a team who are third in South American World Cup qualifying and represent a step up. Expect a comfortable Colombia victory with plenty of goals scored.

Read our full Colombia vs Panama predictions

Uruguay vs Brazil best bet: Both teams to score (-110)

Uruguay breezed into the quarterfinals of the 2024 Copa America, winning all 3 of their games. They scored 9 times across those victories, proving themselves as real contenders to challenge Argentina for this competition. Brazil are struggling for form, having won just once across their last 4 games. They have an impressive squad, but ties against the USA, Costa Rica and Colombia are a concern. The Selecao have seen both teams score in 5 of their last 6 games, while they’ve produced just 3 shutouts in their last 19 matches.

Brazil have enough going forward to trouble Uruguay, who didn’t have a lot of tests in the previous round. However, Uruguay have made a brilliant start in World Cup qualifying too, which included a win over Brazil in October. Both teams have plenty of talent in attack and the best bet of the game is for goals to be scored at both ends.

Read our full Uruguay vs Brazil predictions

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