Week 16 of the 2025 NFL season will begin with a showdown in the NFC West between the Los Angeles Rams and Seattle Seahawks on Thursday Night Football. In fact, the stakes simply could not be any higher. Whoever wins on Monday will not only earn solo possession of first place in the division but will also occupy the #1 seeded spot in the conference.
Here is my Same Game Parlay for the festivities, which get underway at 8:15 pm ET on Amazon Prime. Also be sure to check out our full Rams vs Seahawks predictions when available.
Rams -1.5 (+102)
Under 44.5 (-115)
Kyren Williams to record 60+ rushing yards (+109)
Parlay odds: +525
Part of the value in a Same Game Parlay, of course, is that all of its components can be correlated if you so choose. That is some of the plan here, as Los Angeles running back Kyren Williams racking up his fair share of rushing yards would obviously work well with a Rams victory and cover. At the same time, plays that aren’t correlated drive up the overall payout of the parlay. That is the case with also the under. But even if Williams fares well, there is no reason why the under can’t cash. Let’s break down each of the 3 legs.
Rams -1.5 (+102)
The Rams just might be the best team in the NFC. Heck, they might even be the best team in the entire NFL. A recent loss to Carolina was clearly an aberration, because Los Angeles has otherwise been on an absolute roll since Week 5. Head coach Sean McVay’s squad has won 8 of its last 9 games, a hot stretch that includes victories over 4 opponents that would be in the playoffs if the regular season ended today. That doesn’t even count this past weekend’s 41-34 win over Detroit, a team that is certainly playoff material even though it is currently occupies the first spot out of the postseason in the NFC. This 8-1 run by the Rams is highlighted by a Week 11 victory over none other than the Seahawks – a 21-19 decision in L.A. The home side picked off Seattle QB Sam Darnold 4 times and also limited the ‘Hawks to 3.9 yards per carry. Since its Week 8 bye, the only team with a winning record that Seattle has defeated is Indianapolis (8-6) — which was playing with a 44-year-old under center in Philip Rivers.
Under 44.5 (-115)
To the surprise of no one, this week’s forecast is terrible in the Pacific Northwest. A downpour is expected for Thursday, which certainly wouldn’t be a favorable development for either offense. And even in ideal conditions, the scoreboard would not be expected to light up in this matchup between the Rams and Seahawks. After all, only 40 total points were posted when these 2 division foes squared off 2 months ago in Los Angeles. Neither defense has slowed down much since that result. The Seahawks are #4 league wide in total defense, #2 in points allowed, #3 against the run, #2 in yards per rushing attempt allowed, #7 against the pass, #1 in opponents’ yards per pass attempt, #4 in sacks and #5 in turnovers forced. The Rams are #4 in scoring defense, #9 stopping the run, #8 in yards per pass attempt allowed and #6 in turnovers forced.
Kyren Williams to record 60+ rushing yards (+109)
As good as Matthew Stafford is, moving the ball through the air is not going to be easy on Thursday night – not for either team. One, buckets of rain would be detrimental. Two, Seattle’s pass defense is outstanding. The Seahawks are surrendering only 191.4 yards per contest through the air on 6.0 yards per attempt. Head coach Mike Macdonald’s club is solid against the run, too, but not entirely dominant. Williams should be able to find some running room, just as he did in the previous head-to-head showdown. The Notre Dame product ran for 91 yards and a touchdown on just 12 carries. The ‘Hawks dominated the time of possession by almost 38 minutes to the Rams’ 22; that’s why Williams got only 12 carries. He should get a lot more on Thursday. Williams has already surpassed the 1,000-yard mark in 2025 and has rushed for 72 yards or more in 6 of the past 7 contests.
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