Monday Night Football Predictions: Philadelphia Eagles vs LA Chargers Expert Picks, Odds & Best Bets for Week 14

Los Angeles Chargers wide receiver Ladd McConkey (15) celebrates his touchdown scored against the New Orleans Saints with wide receiver Simi Fehoko (87) during the second half at SoFi Stadium.

Andrew Wilsher

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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.

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Eagles vs Chargers predictions & NFL MNF picks

Chris Farley’s Eagles vs Chargers spread pick: Chargers +3 (-110)

As if losing to the Cowboys in Week 12 wasn’t enough, Philadelphia followed that up with a home loss to the Bears this past Friday. In the process, they looked worse than they have all season. Generating just 6.2 yards per play and converting just 4 out of 12 third downs, another lackluster performance by Saquon Barkley juxtaposed 2 turnovers from Jalen Hurts, who went just 19-34 for 230 yards. Even more startling, the Eagles possessed the ball for only 20 minutes and 42 seconds, just one-third of total game-time.

Perhaps even more surprising was their defense, a group that had been holding up their roster for weeks on end and finally capitulated. The Bears ran it down their throat for all 4 quarters, gaining 281 yards on the ground and 425 total. Chicago correspondingly gained 28 first downs, doubling Philadelphia. Radio personalities in the City of Brotherly Love are anything but loving after that performance, and the Eagles are now a main topic of discussion in the national media. It all feels very 2023, a season where the Eagles completely sputtered at the end of the year, losing 5 of their last 6 games. We wouldn’t be surprised if the exact same thing happened here. Without a formidable rushing attack and top-tier play-calling, Hurts is not the kind of quarterback who can carry his team.

The Chargers had an easy breezy win in Week 13, blowing by the Raiders at home. Beating up on Vegas is hardly an indication of a return to top-form for any program, but it was a nice response after their bye-week. Defensively they’re still among the best, 7th overall in defensive EPA. Offensively LAC remains a middling program, ranked 16th in offensive EPA, and now they’re concerned for Justin Herbert. He had surgery on his left hand on Monday and he’s considered day-to-day. In general, the Chargers have played poorly against great teams, but we can hardly consider the Eagles “great” at this juncture.

The Monday night total is very low and the spread indicates this will probably be a close game. The combination suggests neither offense will pull away, which is largely what we’ve seen this season. The Bolts don’t have much of a home-field advantage, but the ability to stay home for a full week and rest before a big opponent is surely preferable. Meanwhile, Philadelphia will travel across the country and experience the lag of a 3-hour time difference. The Chargers could easily be the favorite in this game, so we have no other choice.

Chris Farley’s Eagles vs Chargers total pick: Under 41.5 (-108)

A very low total is very appropriate for these struggling offenses. We’ll start with the Eagles, although their transgressions are well documented at this point.

After a fast 4-0 start, Philly’s production has slowed down mightily. Since Week 5, they’ve only eclipsed 340 yards in 2 out of 8 contests, and rarely do they have a big game on the ground. Saquon Barkley and his backfield teammates just don’t produce much, good for only 4 yards per carry (24th). Since Week 5, they’ve only eclipsed the century mark 3 times.

That puts a ton of pressure on Jalen Hurts, who’s not built for such a role. We’re not suggesting he hasn’t done great things, but year after year Philly has endured turnover in offensive coordinators, a result that’s finally starting to affect them. Kevin Patullo, who has limited experience in the role, is certainly starting to show his naivete. Philadelphia’s offense ranks just 14th in total EPA, and on Monday they’ll be combating one of the NFL’s best defenses.

The Chargers’ offense isn’t exactly prolific, either. A burgeoning rushing attack has helped keep them afloat. If you take out a very poor all-around outing at Jacksonville back in Week 11, the Chargers ran for 645 yards in their past 4 games. Justin Herbert’s surgery on his non-throwing hand is cause for concern, but LAC’s passing attack hasn’t been stellar either way. They rank 18th in EPA per pass and average 7.2 yards per pass (14th), but lately it’s regressed further. In his last 5 starts, Herbert has thrown for 212, 212, 199, 93, and 149. Woof.

Read NFL pro bettor Chris Farley’s full analysis for his Eagles vs Chargers predictions for MNF, where he is currently on a 12-6 run!

Eagles vs Chargers player prop bets

Best Eagles vs Chargers player prop bet: Omarion Hampton 40+ and Saquon Barkley 60+ rushing yards (+144)

Nick Sirianni has taken over play-calling for the Eagles this week after much has been made about the stale offense of late. For me, I interpret that as a big dose of Saquon Barkley that will open up opportunities for Jalen Hurts in the passing game. On the Chargers’ side, Omarion Hampton’s injury really exposed some inadequacies in the Chargers’ offense, and even though Herbert’s injury is to his non-throwing hand, it’s better to limit his dropbacks when possible.

The total sitting at 42.5 tells me that the game script should lend itself to a battle of the running backs and a key stat on 3rd down is putting me over the edge here — both Philadelphia and Los Angeles are bottom 12 in the league on rushing first downs over the last 3 weeks. These are situations where the rush is obvious, and the defenses were unable to come up with the stop. I’m going to lean on these 2 starting RBs having a big role in a low-scoring affair.

Lock in Prop Holliday’s best MNF player prop bets for Eagles vs Chargers, targeting Omarion Hampton and Saquon Barkley

Eagles vs Chargers TD scorer best bet: AJ Brown (PHI) anytime touchdown scorer (+190)

It’s been a rollercoaster of a season for AJ Brown and the Philadelphia Eagles. Brown struggled amidst the Eagles’ 8-2 start to 2025. Yet, over the last 3 games, 2 being losses to the Cowboys and Bears, Brown has led the league in first-read targets. The Eagles have made an effort to get their #1 receiver the ball, especially in the red zone. During those 3 weeks, Brown has 4 receptions inside the 20-yard line, which ranks inside the top 5 in the NFL. Look for Jalen Hurts to hunt down Brown against a Chargers defense that runs zone at an 82% rate — the 2nd-most in the NFL.

Cowboys vs Lions TNF TD scorer prediction: Ladd McConkey (LAC) anytime touchdown scorer (+250)

The status of Justin Herbert is still in question heading into Monday Night Football. If he does play, you’d expect him to operate in the shotgun with a hand injury as severe as his. Quick hitters to Ladd McConkey and Keenan Allen may be Herbert’s best bet for MNF — especially against a talented Eagles defensive front.

Last week was the Kimani Vidal show against the Raiders, which featured a positive game script. I don’t anticipate another 25 combined carries from Vidal and Omarion Hampton, who is returning from an IR stint, even with Herbert’s injury. So, we’ll turn to McConkey as our 2nd Eagles vs Chargers TD scorer bet, who has found the end zone 5 times in his last 8 games.

After TD scorer winners last week at +500, +425 and +310 odds, make sure you lock in tonight’s Eagles vs Chargers touchdown scorer best bets

Philadelphia Eagles vs LA Chargers Same Game Parlay

After cashing last week’s Bengals vs Ravens TNF SGP, we’ve now hit 4 winners in 4 weeks at +753, +750, +525 and +450 odds! Don’t miss our Eagles vs Chargers SGP for MNF

Chargers ML over Eagles (+120)

It’s starting to feel like the 2nd half of the 2023 season, which went entirely off the rails for Philadelphia. We certainly haven’t reached that point quite yet in 2025, but things are starting to go haywire. The Eagles will still probably win their division because nobody else is any good, but the bottom line is that they aren’t playing well. Even prior to their current 2-game skid, the Birds scored a combined 26 points in unceremonious victories over Green Bay and Detroit. Saquon Barkley is not doing much of anything, Jalen Hurts is struggling and AJ Brown is disgruntled. It’s simply impossible to have any faith in this offense.

Los Angeles had been dealing with its own problems on that side of the ball, but the offensive line is getting healthier and Hampton has recovered from his ankle issue. He immediately gets to face a Philly defense that got run all over by Chicago on Black Friday. Assuming that Justin Herbert will be under center despite a hand injury (non-throwing), LA has great value as an underdog. A home game against an opponent from 3 time zones away will only help the Bolts’ chances.

Omarion Hampton to score a touchdown (+165)

Hampton is finally back from his ankle injury and will play for the first time since Week 5. Before going down, the rookie out of North Carolina had 66 carries for 314 yards and 2 touchdowns in addition to 136 receiving yards. Hampton, a first-round selection, was coming up big for the Chargers. He should pick up right where he left off given that he has a favorable matchup on MNF.

The Eagles’ defense has not been great against the run all season long and was especially poor in that department against the Bears. Philly has surrendered 14 touchdowns on the ground – even more than its 12 passing TDs allowed. In fact, both the Eagles and Chargers are 2 of only 3 teams in the entire NFL who have given up more rushing touchdowns than passing.

Saquon Barkley to score a touchdown (+110)

It’s probably time to give up on Barkley ever turning in the type of huge performances that he delivered so many times during the 2024 campaign. However, asking him to simply get into the end zone on Monday Night Football should not be too much. As mentioned above, the Bolts also allow an unusual number of scores on the ground – 14, compared to 12 through the air. Although Barkley has underwhelmed for the most part this year, he has still produced a respectable 6 TDs (4 rushing, 2 receiving).

Eagles vs Chargers SGP odds: +1000

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