NFL Week 6 MNF Betting Guide: Expert Bills vs Falcons Picks, Bears vs Commanders Predictions & Best Bets

Buffalo Bills quarterback Josh Allen (17) takes the field before the game against the Dallas Cowboys at Highmark Stadium.
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Andrew Wilsher

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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.
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Week 6 of the 2025 NFL season wraps up tonight and we’ve got a Monday Night Football doubleheader to get hyped up for. Things start out with Bills vs Falcons at 7:15 pm ET on ESPN before Bears vs Commanders gets started an hour later at 8:15 pm ET on ABC. And here at Pickswise, we have everything you need to bet better on BOTH MNF matchups! You can find out our NFL picks on the side and total, with our experts boasting a 103-78-1 record with their predictions so far this season for +42.3 units! Plus, don’t miss our NFL player prop bets from Prop Holliday and JutPicks, as well as our Same Game Parlays! Let’s get into our MNF picks and predictions.

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NFL picks & MNF predictions

Bills vs Falcons & Bears vs Commanders best player prop bets

Bills vs Falcons Same Game Parlay and Bears vs Commanders SGP picks

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