Our NFL expert's best player prop bets for San Francisco 49ers vs Minnesota Vikings on Monday Night Football

Brandon Aiyuk of the San Francisco 49ers
Photo of Prop Holliday - Bobby Stanley

Prop Holliday - Bobby Stanley


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NFL and NBA props specialist for Pickswise. For "Prop Holliday" Bobby Stanley media enquiries, please email contact@pickswise.com.

Monday Night Football in Week 7 looked like a playoff matchup back in August. Fast forward 3 months and Justin Jefferson is on IR, Kirk Cousins trade rumors were a constant until he refused to waive his no-trade clause, and the 49ers are coming off a loss (but are still the best team in the NFC). I expect Brock Purdy to bounce back after his worst performance of the season, and the Vikings’ defense in primetime is a perfect opportunity to do just that. Minnesota is 25th in opponent 3rd-down conversion, 26th in red zone scoring and 20th in opponent touchdowns per game. You can read our NFL picks with our experts boasting +32.2 units of profit this season, but for now, let’s get into our 49ers vs Vikings best player prop bets.

Brandon Aiyuk over 65.5 receiving yards (-110)

Line available at Bet365 at the time of publishing. 

Brandon Aiyuk should feast against this Vikings defense that plays an equal amount of man and zone coverage, which is perfect because he posts a top-5 receiving grade against both man and zone coverage this season according to PFF. The 49ers wide receiver has seen no fewer than 6 targets in every game this season and is averaging 18.1 yards per reception. This number just feels low and should take 4-5 receptions to hit, which has been where Aiyuk has lived this season. 1U

Read our full San Francisco 49ers vs Minnesota Vikings predictions

Alexander Mattison under 45.5 rushing yards (-110)

Line available at Bet365 at the time of publishing. 

Aside from the fact that a motivated 49ers defense is a horrifying thought, Mattison has been on the struggle bus all season. His carries range from 8 to 20 and Cam Akers is waiting in the wings to make this a timeshare. At 3.9 yards per carry this season, Mattison would need 12 carries to hit this and a negative game script would make that difficult to come by. Mattison is averaging 69.5 yards per game in wins, but that number drops drastically to 45.3 yards per game in losses. Factor in Akers lurking and I’m rolling with the under. 1U

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