A match between Liverpool and bitter rivals Manchester United tops the bill on Sunday, but before that grudge clash at Anfield, there are plenty more Premier League crackers to look forward to. Here are all of our expert soccer picks for the weekend action in England, with the odds available at FanDuel Sportsbook at the time of publishing.
EPL Best Bet: Bournemouth ML over Crystal Palace (+230)
Sixth versus fourth sounds like it should be a dust-up between two of the Premier League’s big guns and established big-hitters.
However, that’s certainly not the case going into the third weekend of October 2025, when sixth versus fourth pits Crystal Palace and Bournemouth.
These unfancied upstarts are absolutely where they are on merit. Palace get home-advantage favoritism, which is hard to dispute since the last time they played at Selhurst Park, they only went and beat the champs Liverpool 2-1.
But Bournemouth are in inspired nick, unbeaten in five, untroubled by the demands of midweek European football (which Palace have). Andoni Iraola’s men look to be of great value to win at Palace, just as they did on their last trip to London at Tottenham.
EPL Best Bet: Fulham Win or Tie (Double Chance) over Arsenal (+140)
Fulham have given Arsenal plenty of headaches over the last two seasons, and this trip to Craven Cottage might be coming at an awkward time for the Gunners.
Marco Silva’s men beat Arsenal 2-1 at home two seasons back and drew 1-1 at The Emirates last term, indicating they can happily go toe-to-toe with the Premier League leaders and title favorites.
Fulham is unbeaten in five at the Cottage this season with four wins. The Gunners make the short hop across London minus the likes of Martin Odegaard and Noni Madueke, while Swedish international star striker Viktor Gyokeres is on an eight-game drought for club and country.
Arsenal have only failed to win two of 10 matches this season, and Mikel Arteta has them shaping-up nicely to finally get over the line and win the league. However, there will be hiccups en route, and this could potentially be one.
EPL Best Bet: Wolves Draw No Bet over Sunderland (+120)
You can’t wipe the smiles off the faces of Sunderland fans after their surprisingly fast start to life back in the big league, but unfancied Wolves are more than capable of turning a Black Cat grin into a grimace.
Regis Le Bris’ play-off winners are on 11 points, while Vitor Pereira’s Wolves are on two and propping up the table.
Yet there are finally signs of life at Molineux courtesy of back-to-back draws against Tottenham and Brighton, on the heels of a League Cup win over Everton.
Pereira has completely overhauled his starting XI since the early weeks of term, and now they look competitive with a first win just around the corner. Indeed, maybe even as early as Saturday.
EPL Best Bet: Mohammed Salah anytime goalscorer in Liverpool vs Manchester United (-115)
Questions are being asked of the wonderful Mo Salah, and this is the stage where the talented Egyptian can fire back a few answers.
It has definitely been a slow start to the campaign for Salah, who has found the net just three times for Liverpool so far, but the Reds’ ace bagged two for Egypt against Djibouti a week ago. The Pharaohs’ superstar can now set his sights on United, a team he has been the scourge of for the best part of a decade.
Salah has scored 13 times against United and can grab a 14th in a routine Liverpool win.
Sure, Arne Slot’s champions have lost three in a row, but that’s a hiccup that won’t be repeated this season. Manchester United look so unsure of themselves under Ruben Amorim that they are always worth opposing.
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