Caleb Wilfinger
Week 5 of the NFL season will get underway on Thursday Night Football with a showdown in the NFC West, as the Los Angeles Rams host the San Francisco 49ers in a game that could decide first place in the division. This matchup isn’t the best contest of the weekend, but there are still opportunities to make some money on the game, so let’s try to take advantage with our 49ers vs Rams Same Game Parlay picks for TNF, which gets underway at 8:15 pm ET on Amazon Prime Video. Make sure you also keep an eye on our NFL picks for every game this season, with our experts currently boasting a 73-54-1 record for +37.1 units!
Rams -7 (-105)
Over 46.5 (-108)
Puka Nacua anytime touchdown scorer (+100)
49ers vs Rams Same Game Parlay odds: +465
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Los Angeles Rams -7 over San Francisco 49ers (-105)
Even though both teams are 3-1 heading into this game, they certainly feel like they’re going in different directions. After all, the 49ers just turned the ball over a whopping 4 times in a loss to the Jaguars, and the San Francisco offense has been ravaged by injuries to its wide receiving corps and offensive line, to say nothing of Brock Purdy’s injury that sidelined him for a few weeks and certainly could have affected his play last Sunday. Therefore, even though Kyle Shanahan has historically had success against the Rams, Sean McVay’s team is much healthier at the moment and the Rams are playing better on both sides of the ball heading into this one.
It’s certainly on the board that Los Angeles is just 1 play away from being 4-0. In fact, if not for a game against the Eagles, where the Rams blew a 19-point lead in the 2nd half, this would be a team most experts would have pegged as a Super Bowl contender. The Los Angeles offense is easily a top-10 unit in the sport at the moment, with Matthew Stafford in complete command and looking like one of the best quarterbacks in the league. He certainly has the weapons to throw to, as the dynamic duo of Puka Nacua and Davante Adams are proving to be very difficult to contain on the outside. As long as the Rams continue to play mistake-free football, they should be in a good position to win and cover the number against the banged-up 49ers.
Read our full 49ers vs Rams predictions for TNF
Over 45 (-108)
Regardless of which team covers the spread in Thursday’s game, this matchup should be a high-scoring affair. Despite their solid start to the campaign, the 49ers’ defense has been compromised due to the rash of injuries on that unit, and it doesn’t help matters that they’ll finally be facing an offense that can do real damage in all phases of the game. Los Angeles is a formidable opponent, averaging nearly 400 yards per game, while sitting inside the top 10 in EPA per pass and EPA per play, per SumerSports.
On the other side of the ball, Brock Purdy is once again ruled out for San Francisco which means Mac Jones will be back under center. While the 49ers have been inconsistent in the passing game to this point, Jones did have some success against the Saints a couple of weeks ago, can they they still should be able to lean on Christian McCaffrey to produce against a Rams defense that is much weaker against the run (18th in EPA per rush allowed) than against the pass. Let’s take the Over in this NFC West showdown.
Don’t miss Prop Holliday’s best 49ers vs Rams player prop bets as he looks to build on his 7-4 start to the season
Puka Nacua anytime touchdown scorer (+100)
He might not be the flashiest player to watch, but Puka Nacua has arguably been the best wide receiver in the game over the first month of the season. The BYU product should be in a good position to succeed once again on Thursday, especially considering the matchup. Nacua has been unguardable to this point, as he led the NFL in receptions (42) and receiving yards (503) in September.
The 3rd-year wideout is clearly Stafford’s favorite target within this offense, and he should flourish against a 49ers defense that has faced Jacksonville, New Orleans and Arizona in recent weeks; not exactly the most threatening of passing offenses. This is a massive step-up in class for San Francisco’s banged-up defense, and Nacua should find the end zone as a result.
Find out JutPicks’ 49ers vs Rams touchdown scorer best bets for TNF, featuring a pick at +325 odds!
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