Boston Bruins vs Buffalo Sabres Prediction, Odds and Picks for Today, 03/25/26

The Boston Bruins are continuing their quest to secure a playoff spot as they travel to Buffalo to face the Sabres. After losing to the Toronto Maple Leafs 4-2 last night, the Bruins need to quickly put that defeat behind them and focus on this upcoming game. Currently occupying a wild-card spot, they are aware that teams behind them are catching up — so they can’t afford to lose many games as the season comes to a close. They will have a tough challenge ahead and will likely depend on a standout performance from goaltender Joonas Korpisalo.

On the other hand, the Sabres are returning home following a 4-game road trip during which they posted an impressive 3-0-1 record. This team is winning at a pace not seen in Buffalo for over 15 years. While the Sabres currently sit atop their division, the Lightning are only 2 points behind — further motivating them to secure a victory against the Bruins. Given the potential for a high-scoring game, I expect the Sabres to come out on top — and to do so in regulation.

Bruins vs Sabres prediction: Buffalo 3-Way ML (-135) available at time of publishing. Playable at that number.