Buffalo Sabres vs Boston Bruins Prediction, Odds and Picks for Today, 10/11/25

The Boston Bruins are off to a 2-0 start after picking up wins over the Capitals and Blackhawks to open the 2025 season. The Bruins welcome the Buffalo Sabres to town on Saturday night in search of a 3-0 start. Boston’s offense has potted 7 goals through 2 games, with David Pastrnak leading the way to the tune of 4 points on 1 goal and 3 assists. Pastrnak figures to do a lot of the heavy lifting for Boston’s offense yet again this season, but he is more than talented enough to carry the load. With that being said, Elias Lindholm, Morgan Geekie and Pavel Zacha already have multiple points on the season — so some of Boston’s secondary scorers are already chipping in.

The Sabres were held off the scoreboard in their season opener against the Rangers, as Igor Shesterkin posted a 37-save shutout. Don’t be surprised if Buffalo comes out firing, looking to put together a bounce-back offensive performance. The Sabres beat the Bruins 3 times last season, scoring a total of 16 goals in the process. Throw in the fact that both of these teams had questionable goaltending over the course of last season, and both offenses could be in line for strong days in this one. Let’s roll with the over.

Sabres vs Bruins prediction: Over 6 (-110) available at time of publishing. Playable at that number.

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