Buffalo Sabres vs New Jersey Devils Prediction, Odds and Picks for Today, 12/21/25

The Buffalo Sabres are heading to New Jersey to face the Devils in their second matchup of the season. These teams first met on November 28th, when the Devils secured a 5-0 victory. The Sabres have been on a winning streak, securing victories in their last five games. Their goaltending has been solid, which is a significant advantage. Although Alex Lyon has had a fantastic season, he is unlikely to start this game, as it is Buffalo’s third match in four nights.

The Devils have won three of their last five games and are on a two-game winning streak. While their goal scoring has been somewhat limited, their goaltending has been impressive. Jacob Markstrom secured a 2-1 win in Utah, but Jake Allen will likely be in the net this time. Markstrom hasn’t started back-to-back games since mid-November. Allen has a goals-against average (GAA) of 2.49 and a save percentage (SV%) of .912, making him a reliable option.

The Sabres are expected to allow some goals, but it’s unlikely that this game will turn into a high-scoring affair. The Devils have been defensively solid over the past ten days, a trend that seems set to continue. While Buffalo’s offence has improved recently, it remains below average. Therefore, we predict the total score will be under.

Sabres vs Devils Prediction: Under 6.0 (-110) available at the time of publishing. Playable at that number or better.