Detroit Red Wings vs St. Louis Blues Prediction, Odds and Picks for Today, 10/28/25

The Detroit Red Wings are in St. Louis to take on the Blues on Tuesday night. These teams met on Saturday in a wild contest that saw the Red Wings emerge victorious by a score of 6-4. The Blues raced out to a 4-0 lead and looked primed to cruise to a win. But Detroit came storming back and scored 6 straight goals to hand the Blues a demoralizing defeat. The Blues weren’t able to rebound on Monday against the Penguins, as they fell 6-3 in Pittsburgh. St. Louis has now lost 4 games in a row and has to play on the second-half of a back-to-back with travel in this one. That makes this a tough situational matchup for Jim Montgomery’s squad.

The Red Wings are off to a strong start with a 6-3-0 record through 9 games. Dylan Larkin is leading the way with 13 points through 9 games, and Detroit’s young core has impressed thus far. Patrick Kane will be sidelined yet again with an upper body injury, but players like rookie Emmitt Finnie and veteran Mason Appleton have stepped up in his absence. St. Louis goaltender Jordan Binnington owns a less-than-ideal .872 save percentage on the season, and Detroit is more than capable of giving him more issues. This is a tough spot for a Blues team that is reeling, so consider backing the Red Wings on the road.

Red Wings vs Blues prediction: Red Wings ML (-105) available at time of publishing. Playable to -110.