Florida Panthers vs Philadelphia Flyers Prediction, Odds and Picks for Today, 10/13/25

After a pair of 1-goal victories to start the season, the Panthers exploded for a 6-1 win over the Senators on Saturday. Florida is off to a 3-0-0 start without the services of Matthew Tkachuk and Aleksander Barkov, but how long can that success last? Florida still has plenty of scoring depth, but not having two of their top playmakers in Tkachuk and Barkov is still something to consider this early on in the season. Plus, Florida got to play each of its first 3 games at home to open the new campaign. This will be the Panthers’ first road game, and it comes against a new-look Flyers team that is capable of pulling an upset.

Philadelphia and Florida met last week, with the Panthers winning by a score of 2-1. The Flyers then went to Carolina and lost to the Hurricanes 4-3 in overtime. They have yet to find the win column, but the Flyers have given two tough opponents all they can handle to start the season. Not only is this matchup the first road game for Florida this season, but it’s the home opener for the Flyers. With that in mind, don’t be surprised if Philadelphia finds the win column for the first time this season in this one.

Panthers vs Flyers prediction: Flyers ML (+120) available at time of publishing. Playable to +115.

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