Buffalo Sabres vs Ottawa Senators Prediction, Odds & Picks for Today, 10/15/25

The Ottawa Senators travel to Buffalo to take on the Sabres for the first time this season. Ottawa comes into this matchup scoring just 2.67 goals per game and will be without their captain, Brady Tkachuk, for at least the next 4 weeks. He suffered an injury against Nashville, but the details haven’t been released. To make matters even worse, they are giving up 4.67 goals per game. It’s been a rough start for a team that had high expectations of going back to the playoffs this season.

As for Buffalo, this has to be the bottom of the market, right? They have scored just 2 goals in their first 3 games, that’s good for just 0.67 goals per game. The Sabres are are missing their starting goalie due to injury, as well as Josh Norris, who is out long-term with an upper-body injury. At some point, things will need to improve, but it may not happen tonight. Both these teams are going to struggle to generate offense, so the Under is very much in play. Goaltending could let us down, but that’s a risk we are willing to take.

Senators vs Sabres prediction: Under 6.0 available at the time of publishing. Playable at that number or better.

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