Tampa Bay Lightning vs Buffalo Sabres Prediction, Odds and Picks for Today, 04/06/26

When the Lightning and Sabres met a little less than a month ago on March 8, the Sabres walked away with a wild 8-7 win in what was arguably the game of the year in the NHL so far this season. Both offenses were firing on all cylinders, which follows a common theme for Tampa Bay and Buffalo in their 3 meetings this season. All 3 games have gone over the total, with 7, 8 and 15 total goals being scored. I expect that trend to continue in Monday night’s matchup at KeyBank Center in Buffalo.

The Sabres have scored just 3 total goals over their last 2 games, but after playing both of those games on the road, they now return home where they rank fifth in the NHL by scoring 3.50 goals per game. Furthermore, the Buffalo powerplay is clicking at a 25% clip on home ice — which is good for sixth in the league. The Lightning enter this contest rolling on offense, as they have potted an average of 4 goals per game over their last 10 outings. Both of these teams play with great pace and are excellent at creating Grade-A scoring chances. Look for this matchup to put plenty of pressure on the goaltenders. The over is the play.

Lightning vs Sabres prediction: Over 6.5 (-110) available at time of publishing. Playable at that number.

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