The Chicago White Sox are utilizing an opener on Wednesday, and their offensive form is worse than Kansas City’s recently, but I still favor Chicago in this spot. Bryan Hudson is set to open the game for the White Sox, marking his 68th appearance and 9th time opening a game this season. Hudson has performed well for Chicago in 2026, posting a 3.03 ERA in his 65.1 innings of work. His last outing resulted in 2 earned runs and 2 outs recorded, but his previous 11 outings had each resulted in scoreless performances. Hudson should be able to deliver a strong first inning for Chicago before handing the ball off to Erick Fedde.
Fedde is set to make his 33rd appearance of the season, and he enters this matchup in good form. His last 6 outings have spanned 28.2 innings with just 5 earned runs allowed. In that span, the right-hander has allowed only 20 hits and 1 home run. Kansas City is seeing the ball well offensively across the last stretch of play, but I look for Fedde to continue his strong form in this spot.
Seth Lugo is the scheduled starter for the Royals on Wednesday. Lugo enters play with a 5.06 ERA through his first 31 starts. Health has not been an issue for the veteran right-hander, but his 5.09 xERA supports his struggles on the mound. He ranks 7th percentile in xBA thanks to a 15th-percentile hard-hit rate. Lugo rarely issues walks, but struggles to earn whiffs as well, and he puts a ton of pressure on the defenders behind him to consistently make plays. I favor Chicago in this game at current pricing.
White Sox vs Royals prediction: Chicago ML (-113) available at time of publishing. Playable to -120.
