College Football parlay picks: Week 12 four-team parlay pays 12/1!

Indiana Hoosiers quarterback Michael Penix Jr.
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Matthew Lowrimore


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Matthew has been with Pickswise for a while now, covering a wide variety of sports. His main passions are college football and UFC, and those are the sports he has covered the most. Matthew uses a variety of methods to handicap games, including stats, trends, injuries, and situational factors. His goal is to consistently give out winners and will put in the research to try and achieve this.

Week 12 College Football action is here! A College Football parlay is a great way to incorporate several games from a huge slate of action and have some fun with the chance of hitting big. Three sides and one total pays huge odds of +1228 with FanDuel Sportsbook.

Let’s get into Saturday’s free College Football parlay picks. Feel free to add, subtract or mix and match plays which you like!

Indiana Hoosiers +20.5 (-110) vs. Ohio State Buckeyes

These are the two best teams in the Big Ten and should be an awesome game to see. The Indiana Hoosiers are legit and deserve to be a top 10 team. They have been amazing on both sides of the ball. Offensively, quarterback Michael Penix Jr. has been playing unreal and has a 9-3 touchdown to interception ratio. The Hoosiers offense is stacked with weapons like Stevie Scott III, Ty Fryfogle, Whop Philyor, and Peyton Hendershot. Defensively, Indiana is plus eight in the turnover battle this season and has only allowed 19.25 points per game. This has led to Indiana being 4-0 straight up and against the spread.

Ohio State is a fantastic team but has not played a good team yet. This is going to be Ohio State’s toughest opponent for the year and the committee can pencil in the winner of this game for the College Football Playoff. The Buckeyes’ defense has not been too impressive this season. With a spread this big the Buckeyes have to be perfect to cover but this Indiana team is too good to let them play a perfect game. Expect the Hoosiers to keep this game close and cover this massive spread. Take the Hoosiers in this marquee matchup.

Clemson Tigers vs. Florida State Seminoles Over 64.5 Points (-110)

These teams have been hitting the over consistently with Florida State hitting the over in five out of their last six games and Clemson hitting the over in each of their last four games. In the Trevor Lawrence era at Clemson, their offense averages 36 points per game after a bye week. Florida State’s defense is in free fall and that should continue against one of the best scoring offenses in the nation. Clemson should score anywhere from 50 to 60 points by themselves.

For this to go over, all Florida State has to do is score 14 points and play no defense which is very likely even if starting quarterback Jordan Travis is not playing. Travis Etienne will have a huge game and break multiple runs open that allow Clemson to top 50 points. Trevor Lawrence is looking to come back strong after missing two games and lost their number one ranking. Expect Clemson to have whatever they want offensively and push the total over the number.

Kentucky Wildcats +29.5 vs. Alabama Crimson Tide (-110)

Kentucky has some of the weirdest results of any team this season. They are under .500 at 3-4, but at times they have looked dominant, beating Mississippi State and Tennessee by a combined score of 58-9. Somehow last week they gave up 35 points to Vanderbilt though, and that has to be concerning with Alabama, one of the best offensive teams in the country up next.

Alabama has had two huge numbers to try and cover this season, -28.5 in the opener against Mizzou, and -29 last week against Mississippi State. They did not cover against the Tigers, winning by just 19, and I think that is the way this one is going to play out — a very comfortable win but no cover here for the home team. That Mizzou team was probably just as lame offensively as these Wildcats are because that was before they found their freshman QB.  As long as Kentucky can get a couple of scores this one is likely to stay within range of the number.

Michigan Wolverines vs. Rutgers Scarlet Knights +10.5 (-110)

Both the Rutgers Scarlet Knights and Michigan Wolverines will be hoping to halt three-game losing streaks when they collide at SHI Stadium on Saturday night. Head coach Jim Harbaugh’s squad is coming off consecutive setbacks at the hands of Michigan State, Indiana, and Wisconsin. It has lost its last two contests by a combined margin of 87-32.

Let’s not get carried away by thinking that the Scarlet Knights are good, but they at least won at Michigan State by 11 points and were respectable enough against Indiana and Ohio State before losing to Illinois 23-20. Michigan quarterback Joe Milton has as many touchdowns as interceptions (four apiece) this season. He isn’t helped by the fact that his team has no semblance of a running game. Rutgers is 4-1 ATS in its last five following a loss. Take the Scarlet Knights and the points without hesitation.

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