NFL Odds for Divisional Round: Playoff Lines, Spreads & Totals This Week

Following a wildly entertaining Wild Card Weekend, the stage is set for the Divisional Round of the NFL Playoffs. Eight teams remain in search of the Lombardi Trophy, giving us 4 can’t-miss matchups on Saturday and Sunday.   

Make sure you check out our NFL predictions as we add our picks on the side and total for every game throughout the week – and throughout the entire playoffs. Also, make sure to check out our NFL best bets page for our top picks. For now, let’s break down the NFL Divisional Round opening lines and give our best early bet to make.  

NFL Divisional Round opening lines and odds  

Odds available at DraftKings Sportsbook at time of publishing  

• San Francisco 49ers +7 (-105) vs Seattle Seahawks -7 (-115) – Saturday 

• Buffalo Bills -1.5 (-105) vs Denver Broncos +1.5 (-115) – Saturday 

• Los Angeles Rams -3.5 (-112) vs Chicago Bears +3.5 (-108) – Sunday 

• Houston Texans +2.5 (-104) vs New England Patriots -2.5 (-118) – Sunday 

Best bet for the Divisional Round: Houston Texans vs New England Patriots Under 41.5 (-110) 

As expected, both defenses were incredible during Super Wild Card Weekend. New England held the Chargers to just 3 points on Sunday; Houston gave up only 6 points to Pittsburgh on Monday. Both teams forced 2 turnovers. The Patriots came up with 6 sacks, while the Texans took down Aaron Rodgers 4 times. This is nothing new, either – especially for the Texans. In the regular season they were #1 in total defense, #2 in scoring defense, #6 against the pass, #3 in interceptions and #6 in sacks.

On the other side of the ball, don’t be fooled by Houston’s 30 points against the Steelers. The Texans’ offense was horrible almost the entire game and 2 of the team’s TDs were scored by the defense. Moreover, wide receiver Nico Collins may be sidelined by a concussion. Meanwhile, New England scored a mere 16 points in its wild-card game. Count on defense dominating this matchup from start to finish. I really don’t see either team getting to the 20-point mark on Sunday.