Week 15 NFL best bets, odds and predictions: Chiefs and Mahomes take out their anger on Patriots

Oct 22, 2023; Kansas City, Missouri, USA; Kansas City Chiefs quarterback Patrick Mahomes (15) takes the field prior to a game against the Los Angeles Chargers at GEHA Field at Arrowhead Stadium. Mandatory Credit: Jay Biggerstaff-USA TODAY Sports
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Andrew Wilsher

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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email contact@pickswise.com.
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We have just 4 Sundays left in the 2023 NFL regular season with Week 15 upon us, and things are really beginning to heat up. There are still tons of teams in contention for a wild-card spot in both the AFC and NFC, and there will no doubt be plenty of motivation heading into this weekend with a lot of teams factoring in a win-or-go-home mentality. We’ve got a tripleheader on Saturday, for which we have an NFL best bet for one of the games, along with a strong Sunday slate to keep the great football action rolling all weekend long.

Our NFL handicappers have been red-hot this season, as they boast a 43-30 record with their 3-star best bets which has returned +21.99 units of profit! It’s been a similar story on our NFL picks for every single game, as we currently boast a 223-187-7 record for +39.2 units. Let’s continue helping you to bet better and dive into our NFL best bets for Week 15.

The Betting Queen: Indianapolis Colts ML over Pittsburgh Steelers (-110)

The Pittsburgh Steelers will be visiting the Indianapolis Colts for some Saturday football at Lucas Oil Stadium. Both of these teams are coming off a loss last Sunday, but the Steelers are the team in more trouble. They will be starting backup quarterback Mitchell Trubisky, as Kenny Pickett will sit out another week with an injury. This Steelers offense has been one of the worst in the league this year, averaging fewer than 17 points per game; somehow they still have a winning record. If the Steelers want to have a chance to win, they will need to get the ground game going with Najee Harris and Jaylen Warren. I’m looking for the Steelers’ offensive struggles to continue and for points to be few and far between.

Although the Colts are coming off a loss on Sunday, they had won 4 straight games prior to that. Gardner Minshew has really stepped up as a starting quarterback ever since rookie Anthony Richardson got hurt. Minshew has had no trouble finding Michael Pittman Jr. all year and is having his best statistical season in the NFL. Star running back Jonathan Taylor will miss his third game with a thumb injury and Zack Moss will have to try to pick up the load once again. The Colts have the better offense on paper and also the better team. The only reason why this game is close to a pick ’em is because they both have the same record and a backup quarterback under center. The Colts have the advantage on every level and it will probably show on Saturday. I’m backing Indy on the money line with confidence.

Be sure to check out our full Pittsburgh Steelers vs Indianapolis Colts predictions

Andrew Ortenberg: Atlanta Falcons -3 over Carolina Panthers (-110)

The Carolina Panthers will look to pick up their 2nd victory of the season here as they host their division rival, the Atlanta Falcons. Unfortunately for Bryce Young, I don’t think he’ll be getting his 2nd win here. The Panthers are clearly the worst team in the league, and they couldn’t keep it close against New Orleans last week despite Derek Carr being dreadful from start to finish. They lost 28-6 to the Saints, and Young somehow manages to keep looking worse.

To say it’s been a disastrous rookie season for the first overall pick would be a massive understatement, and there are very few bright spots on this team. Carolina’s last 2 home games were a 23-point loss to the Cowboys and a 14-point loss to Gardner Minshew and the Colts, so I don’t think we can give them much credit for home-field advantage. Not when tickets to the game are selling for less than a dollar on various marketplaces, as people on X were quick to point out this week.

In typical Falcons fashion, they’ve lost themselves some games they should’ve won, but overall I’m more bullish on this Atlanta team than most. Each of their past 4 losses have come by 5 points or less, and their record could easily be a lot better if a few balls had bounced their way. Desmond Ridder has quietly been a lot better than he’s given credit for, and he threw for 347 yards (8.7 YPA) last week against the Bucs. And we all know they’ve got plenty of skill position talent with guys like Bijan Robinson, Kyle Pitts and Drake London in the lineup. When these teams played back in Week 1 the Falcons picked up a dominant 24-10 win, and I think we could see something similarly lopsided here.

Be sure to check out our full Atlanta Falcons vs Carolina Panthers predictions

Chris Farley: Kansas City Chiefs -9.5 over New England Patriots (-110)

The entire football world is still talking about Kadarius Toney and how far offsides he was or whether it should have been a penalty at the end of the Bills-Chiefs battle. I could care less. The reality is, for our wagers only 1 thing matters: the Chiefs are FIRED up. Chris Jones was caught yelling at defensive coaches, coaches were slamming play-sheets, Patrick Mahomes was chasing down referees at the end of the game…it was mayhem at the end of the Chiefs’ Week 14 loss. But those are the situations I love to capitalize on the following week. We have missed a few times on Kansas City this season (who hasn’t!?!?), but this team has endured many unfortunate circumstances. Whether it has been an errant call or a barrage of dropped passes by the KC receivers, the offense have been through one of the more tumultuous seasons of Mahomes’ 6-year reign as their starting QB. The Chiefs still sit in 1st place in the AFC West, although they are now only 1 game up on the 7-6 Broncos. Things are getting more interesting, but that creates a perfect blend of motivation for an angry Kansas City squad on Sunday.

I like the Chiefs even more because the Patriots finally found success in Week 14. Following nearly 2 months of some of the most unwatchable football anyone has ever seen, Bailey Zappe and the Pats got an ugly win at Pittsburgh last Thursday night. Taking advantage of a sloppy Mitch Tribusky and another sluggish presentation from the Steelers’ offense, New England held the home team to only 264 total yards. It was about as good as it’s going to bet for the 3-10 Patriots, who now return home to likely celebrate the holidays early since they have a tough Week 16 road trip out to Denver after facing KC. One decent game isn’t going to make me think the Patriots can compete with the Chiefs, especially not in their current state of mind. The time for experimenting or “working things out” is over for Kansas City. There is no QB-coach tandem I trust more than Mahomes and Andy Reid; there’s simply no other way I can look with the spread under 10.

Be sure to check out our full Kansas City Chiefs vs New England Patriots predictions

John Martin: Jacksonville Jaguars +3.5 over Baltimore Ravens (-120)

The Jaguars are stuck in the mud right now, having lost 2 straight games and multiple players along the way. Wide receiver Christian Kirk is done for the season. Starting left tackle Cam Robinson is still on injured reserve. Running back Travis Etienne hasn’t looked like his usual explosive self. But this has to be a play on the number for both teams. This number is too expensive to lay with the Ravens, who scraped by the Rams in overtime at home last week but lost do-everything safety Kyle Hamilton for at least a week in the process. Oh, by the way, they play the San Francisco 49ers next week. There are times when the Ravens look like the most dominant team in the NFL, and then there are examples like last week when they gave up 31 points in regulation at home.

Meanwhile, the Jaguars are desperate for a win. That doesn’t guarantee they will win, but there’s a good chance the urgency will be higher on the Jacksonville side. The Jaguars will likely win the AFC South, but they certainly haven’t clinched. This is also a Jags team that scored 27 points on one of the most dominant home defenses in the NFL last week against the Browns, even if they didn’t get the result. Trevor Lawrence is also going to have an additional week of rest for his ankle, which should help him exploit the unpredictable Ravens’ defense with his legs. In a desperate spot at home and with the Ravens looking ahead to San Francisco, we’ll happily take the 3.5 points with the Jaguars.

Be sure to check out our full Baltimore Ravens vs Jacksonville Jaguars predictions

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