Colorado Avalanche vs Los Angeles Kings Prediction, Odds and Picks for Today, 10/07/25

The Colorado Avalanche open the season on the road, and it will be the final home opener for Los Angeles Kings superstar Anze Kopitar. Colorado will be without Mackenzie Blackwood, its starting goaltender, as he is dealing with a lower-body injury. Veteran backup Scott Wedgewood is expected to start, with Trent Miner serving as the backup. Blackwood won’t even travel for the game. That’s the bad news. The good news is that Gabriel Landeskog will play his first regular-season game since March 10, 2022. He got a taste of game action and speed in the playoffs, returning from a very lengthy absence due to a knee injury.

The home team won each of the 3 regular-season meetings in 2024-25, including a 5-4 win by the Kings at Crypto.com Arena in the only H2h date last season in Southern California. The home side has won 5 in a row in this series since Dec. 3, 2023, too. Based on the home-team trends in this series both last season and in the past 5 installments, as well as the fact Colorado will be using its backup goalie, I will side with the Kings on the money line. They should win it for Kopitar in his final regular-season opener at home.

Avalanche vs Kings prediction: Los Angeles ML (-110) available at time of publishing. Playable to -120.

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