Colorado Avalanche vs St. Louis Blues Prediction, Odds and Picks for Today, 04/07/26

For the second time in three days, the Colorado Avalanche and St. Louis Blues hit the ice in the NHL. These Central Division opponents played on Sunday in a 3-2 Blues win, which went a long way for their slim but alive playoff hopes. How will this one shake out? Here is our Avalanche vs. Blues prediction to help find out.

It is well-known that Colorado is a front runner for this year’s Stanley Cup, but they need to regain some momentum as the season closes. They are now 2-3-0 in their last five games, which includes three regulation losses on home ice to teams not currently clinched in the playoffs. I expect a better effort from this team who can typically score 3+ goals, and return the favour of a loss as a road team. They have also been elite on the road at 26-7-5. St. Louis is now 6-1-2 in their last nine games, but not many teams could beat Colorado in two-straight games. We are siding with Colorado for our Avalanche vs. Blues prediction.

Avalanche vs. Blues prediction: Colorado Avalanche money line (-155) available at time of publishing. Playable to (-170).

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