Edmonton Oilers vs Florida Panthers Prediction, Odds and Picks for Today, 11/22/25

The Edmonton Oilers and Florida Panthers square off for a rematch of the 2024 and 2025 Stanley Cup Finals. This is the first time these two will meet since Game 6 of the Stanley Cup Finals where the Panthers won 5-1, winning it all. Neither has performed up to standard so far this season, and in what should be a dramatic battle, one may kickstart a run of strong play. Here is our Oilers vs. Panthers prediction.

Edmonton is 1-3-1 in its last 5 overall and has won just 9 of 23 games. It has been a trying season, and I don’t expect things to get easier on the road against Florida. The Panthers have been formidable on home ice, posting a record of 8-2-1. On Saturday night welcoming a huge recent rival, energy should be extremely high for both the team and the building. They have won four of their last five games, and look like they are regaining their dominance after a 2-5-1 run in mid-October. We have yet to see this from Edmonton all season. Florida is currently running a far more impressive product than Edmonton, and I expect these ways to continue in a key matchup. For this Oilers vs Panthers prediction, I’m going with Florida.

Oilers vs Panthers prediction: Florida ML (-135) available time of publishing. Playable to -150.

Now you can bet any of our Oilers vs Panthers predictions at FanDuel Sportsbook, which has a great new-customer offer to take advantage of. If you sign up for FanDuel right now, you earn a welcome bonus worth up to $150 if your first wager is a winner! Use this link 🔗 to join FanDuel right now and learn more.