Florida Panthers vs St. Louis Blues Prediction, Odds and Picks for Today, 01/29/26

The Florida Panthers and St. Louis Blues meet as part of an action-packed Thursday in the NHL. This is the second and final meeting of the season, and we are here with our Panthers vs. Blues prediction to get you set for the game.

After a regulation loss in their last game, the Panthers concluded a 3-game winning streak. However, I think they are bound to start a new one when all is said and done in this game. The Blues should not pose a major threat to the Panthers, even on home ice where they have won just 43% of their games. This is especially tough as their forward core is extremely injured. Robert Thomas and Dylan Holloway will be out of the lineup, with Jordan Kyrou and Jake Neighbours questionable. They have now lost five-straight games and have been outscored 20-10 over that span. They have no momentum, and are welcoming in a two-time defending Stanley Cup winner with lots of work to do in the standings. Plus, Florida will keep in mind the fact the Blues pumped them 6-2 in front of their home crowd. A favor they will like to return in this matchup. For our Panthers vs. Blues prediction, we are leaning heavy on Florida to get it done. 

Panthers vs. Blues prediction: Florida Panthers ML (-160) available at time of publishing. Playable to (-190).

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