New York Islanders vs Buffalo Sabres Prediction, Odds and Picks for Today, 12/20/25

Saturday evening in the NHL brings us an Eastern Conference matchup between the New York Islanders and Buffalo Sabres. These opponents have met

It has been a strong season for New York led by the excitement of 2025 first overall pick Matthew Schaefer. However, they have now lost two-straight games, and are playing in the second half of a back to back.

Buffalo meanwhile has been on a heater as of late. They currently sit tied for last in the Eastern Conference, but have won four-straight games and have outscored opponents 15-9. They are looking strong, building momentum, and will have home ice in this game, where they have won two-straight games and four of the last five in front of their home crowd. I expect them to keep this momentum, as it was extremely needed after a poor start to the season. There is still lots of time for them to make something of this season, so every win counts. For our Islanders vs. Sabres prediction, take Buffalo on the money line.

Islanders vs. Sabres prediction: Buffalo Sabres money line (-165) available at time of publishing. Playable to (-180).

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