Ottawa Senators vs Anaheim Ducks Prediction, Odds and Picks for Thursday, 11/20/25

The Ottawa Senators kick off a 7-game road trip against the Anaheim Ducks at Honda Center in Southern California. The Senators are coming off a 1-0 loss at home against the Los Angeles Kings, and they are 4-2-3 across the past 9 games. Five of those games have either gone to overtime or a shootout, with 3 losses in OT, a win in overtime and a victory in a shootout. Six of the 9 games are 1-goal games, too. The Senators won the most recent meeting last season on December 11, 2024, splitting the regular-season series. The Ducks have won 3 of the past 4 in the series, while going 7-3 in the past 10 meetings since Feb. 4, 2020.

Anaheim has picked up a pair of victories over the Utah Mammoth and Boston Bruins since a 3-game skid on the road. At home, the Ducks have skated away with 6 straight victories on The Pond since losing October 16 against the Carolina Hurricanes. The Ducks have outscored the opposition 27-12 in the win streak at home. It’s shocking to see that the Ducks are underdogs at home given their dominance in the series and impressive play at Honda Center lately. The Ducks don’t have any notable injuries, so there’s no reason to get away from Anaheim.

Senators vs Ducks prediction: Anaheim Ducks ML (+105) at time of publishing. Playable to -120.

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