Ottawa Senators vs Boston Bruins Prediction, Odds and Picks for Today, 11/06/25

The Ottawa Senators hit the road to battle the Boston Bruins at TD Garden on Thursday night, and the B’s will be looking for redemption. Boston has won 4 consecutive games, but its last loss was a 7-2 setback in Canada’s capital city against the Senators on October 27. In fact, that’s the only loss for the Bruins in the past 6 games dating back to October 23. Boston also lost 3 of 4 in the season series in 2024-25. The Sens have had no issues scoring goals in this series lately, too, outscoring the Bruins 25-15 in the past 6 meetings since April 16, 2024.

The Senators suffered a 4-3 loss in overtime against the Montreal Canadiens last time out on Saturday, and that’s another reason to like the visitors. Ottawa will be well rested, getting a chance to mend some early-season bumps and bruises. Ottawa has rung up at least 3 goals in each of the past 5 games, while averaging 4.1 goals per game in the past 10 outings since October 15. The over is 8-2 in the 10-game span, too, in case you’re looking for a Same-Game Parlay opportunity. Let’s roll with the Senators to maintain their mastery over the Bruins.

Senators vs Bruins prediction: Ottawa Senators ML (-130) at time of publishing. Playable to -140.

You can bet on our Senators vs Bruins pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!