Ottawa Senators vs St. Louis Blues Prediction, Odds and Picks for Today, 11/28/25

The Ottawa Senators and St. Louis Blues meet on Friday night in the NHL. These teams have been playing at a far different level from each other, which has them sitting in very different spots within the league. St. Louis is returning to home ice for the first time in 5 games, but will this be enough of a boost against a surging Senators team? Here is our Senators vs. Blues prediction.

Ottawa has looked great as of late. A stretch of 7-2-3 has them sitting second in the Atlantic Division and gunning for first place. They are a dynamic team filled with skill, and will not be looking to let this great positioning go to waste. Ottawa has outmatched St. Louis in many major categories, including goals per game (3.13 to 2.63), power play (23% to 22.6%), and goals against average (3.22 to 3.58). When you look at the rosters they may seem somewhat similar, but the on ice production tells a different story. I think the Blues are in for a tough matchup, and won’t yet be able to change their losing results. For our Senators vs. Blues prediction, take Ottawa on the money line.

Senators vs. Blues prediction: Ottawa Senators ML (-115) available at time of publishing. Playable to (-130).

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