Philadelphia Flyers vs Buffalo Sabres Prediction, Odds and Picks for Today, 12/18/25

The Philadelphia Flyers and Buffalo Sabres meet as part of a busy Thursday in the NHL. These Eastern Conference teams play their 2nd of 3 meetings, as the Sabres look for payback from a 5-2 beatdown in early-December. Here is our in-depth Flyers vs. Sabres prediction.

Philadelphia continues an impressive and surprising season so far. At 17-9-6, the Flyers are 3rd in the Metropolitan Division, and just 6 points from first in the Eastern Conference with 1 game in hand. There is a new found confidence within this team, and while they are on the road, I expect it to continue. A short road trip has them entering Buffalo, who has experienced yet another poor season. The Sabres just fired their general manager, and while they have won 3-straight games, I am not convinced they will turn this into a run. All games were close, and it cannot be forgotten they were blown out to a bottom-feeding Calgary Flames team 7-4 just 4 games ago. Philadelphia is riding with confidence and momentum, and the Flyers have looked well-balanced on the ice. Take them as underdogs on the money line for our Flyers vs. Sabres prediction.

Flyers vs. Sabres prediction: Philadelphia Flyers money line (+125) available at time of publishing. Playable to (+100).

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