St. Louis Blues vs Colorado Avalanche Prediction, Odds and Picks for Today, 04/05/26

The St. Louis Blues and Colorado Avalanche meet for a Sunday night, Central Division matchup in the NHL. These teams have played just once this season, in a 6-1 blowout win for Colorado. How will this one play out? Here is our expert Blues vs. Avalanche prediction.

Colorado continues to lead the NHL with 110 points, but some very recent play should have them striving for some cleaner play. They are 2-2-0 in their last 4 games, which also included giving up 8 goals to the NHL’s worst team in the Vancouver Canucks. They bounced back perfectly in a 2-0 win against an elite Dallas Stars team, and while they now play in their second in as many nights, they should have the legs to keep up to momentum. St. Louis is 5-1-2 in their last 8 games, but a playoff appearance this season would be miraculous at this point. Colorado is an absolute juggernaut that scores at the league’s highest rate (3.76 per game), allows the least amount of goals (2.49 per game), and own the second-best penalty kill (83.6%). They are also elite on home ice, with a 24-8-5 record. This is too tall a task for St. Louis. I expect Colorado to win in regulation for our Blues vs. Avalanche prediction.

Blues vs. Avalanche prediction: Colorado Avalanche 3-way ML (-135) available at time of publishing. Playable to (-150).

You can bet on our Blues vs. Avalanche pick at DraftKings Sportsbook, which has thousands of betting options available and a great new customer offer where you can get $200 in bonus bets INSTANTLY when you make a first bet of just $5! Click here 👈🏼 to sign up for a DraftKings account now.