Vancouver Canucks vs Pittsburgh Penguins Prediction, Odds and Picks for Today, 10/21/25

The Vancouver Canucks and Pittsburgh Penguins clash on Tuesday night in the NHL. This is the first of two matchups this season, and with both teams at 4-2-0, it is an early season win they would like to capture. Each team has mixed opinions on expectations, but within the organization know that the playoffs are obtainable. To get you set for the matchup, here are our

Canucks vs. Penguins predictions.

Both teams are on respective winning streaks, have the same record, and have similar expectations, so it is no surprise that this game is seen as a coin flip. My choice for this game is the Penguins. This is Vancouver’s fourth-straight road game, which has had them traveling all over the country. The Penguins have been waiting for them on an extra day of rest, and I believe should be highly motivated to build a three-game winning streak. Pittsburgh has been getting far better contributions from their top players as well.  Four players have 5+ points, and their go-to forwards in Sidney Crosby (7 points) and Evgeni Malkin (9 points) have looked excellent. This may be the final kick at the can for this veteran-filled roster, and so far this season they have showed they are willing to put in the work. I think their efforts in this game get them a win. Take Pittsburgh on the money line for these Canucks vs. Penguins predictions.

Canucks vs. Penguins prediction: Pittsburgh Penguins money line (-110) available at time of publishing. Playable to (-120).

You can bet on our Canucks vs. Penguins pick at DraftKings Sportsbook, which has thousands of betting options available and a great new customer offer where you can get $200 in bonus bets INSTANTLY when you make a first bet of just $5! Click here 👈🏼 to sign up for a DraftKings account now.