Tottenham Hotspur vs Atletico Madrid Prediction, Odds and Picks for Tomorrow, 03/18/26

Atletico Madrid have one foot in the Champions League quarterfinals after a resounding 5-2 win over Tottenham in the Spanish capital last week, and they can finish the job with a victory in London on Wednesday. Spurs followed up that mauling in Madrid with an impressive point against Liverpool at Anfield that was thoroughly deserved, but they remain winless under Igor Tudor and have gone 8 games without a victory across all competitions – losing 6 of those games. The tie already looks beyond Tottenham and Premier League survival has to be their priority, and Atleti can ensure they only have that target to focus on by ending their European bid with a defeat.

Los Colchoneros have managed just 1 win in 5 attempts away from home in the Champions League this season, but this trip offers a chance to improve on that record. An injury hit Tottenham team had to dig deep against Liverpool, whereas Atleti had an easier time of it in a 1-0 win over Getafe in their domestic assignment at the weekend. The hosts have a lengthy injury list, including some recent additions as Cristian Romero and Joao Palhinha are unavailable on Wednesday, and key forward Richarlison is suspended.

Atletico Madrid are in form with 6 victories in their last 7 games and they should get plenty of chances on the counter as Spurs have to take risks with a big deficit to recover. Taking that into account, Atleti look capable of beating a weakened Tottenham team who will have one eye on the weekend’s crucial clash with Premier League relegation rivals Nottingham Forest.