Chelsea vs Barcelona Prediction, Odds and Picks for Today, 11/25/25

Chelsea host Barcelona in clash of 2 clubs that sit just outside the top 8 of the Champions League standings at the halfway mark in the league phase. Both teams dropped points on matchday 4 to fall away from the leading pack, with Chelsea held to a 2-2 tie in Azerbaijan by Qarabag while Barcelona battled back from 3 deficits to draw at Club Brugge. They both come into this clash on the back of solid domestic wins, with the Blues having beaten Burnley 2-0 on Saturday and the Blaugrana battering Athletic Bilbao 4-0 in their first game back at Camp Nou. The scoreline does not tell the full story of that game, however, as Bilbao had a couple of great chances to equalize in the first half and were undone by some poor discipline and poor goalkeeping on the day.

Hansi Flick’s team can be a nightmare to play against when they are all on the same page and firing, but they have missed some creativity on the left from Raphinha and spark in the middle from Pedri. The Brazilian made his comeback on Saturday as Marcus Rashford missed out through illness and it looks like Pedri may have recovered from a muscle tear in his left thigh in time for the trip to Stamford Bridge. Their returns make this a tricky game to call because they bring a lot of quality, but the scales still look to be tipping Chelsea’s way. Enzo Maresca’s Blues are on a roll at home with 4 wins in their last 5, including 2 Champions League wins over Ajax and Benfica, plus a big Premier League victory against Liverpool. Take Chelsea to earn a big home win.

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