Newcastle United vs Benfica Prediction, Odds and Picks for Today, 10/21/25

Newcastle’s return to the Champions League has embodied the rest of their season, with consistency proving hard to come by for Eddie Howe’s side. The Magpies have alternated between wins and losses in their home matches this season and the same is true of their Champions League outings as they followed up a narrow 2-1 defeat to Barcelona with a 4-0 rout of Union Saint-Gilloise. That victory in Belgium should have them feeling confident ahead of a visit from Jose Mourinho’s Benfica, but Howe’s side had their momentum dented by Saturday’s 2-1 defeat at Brighton, and their lack of fluency could see them forced into a cagey encounter with the Portuguese giants.

Scoring goals clearly wasn’t an issue for the Magpies in Anderlecht but Mourinho’s tactics need no introduction and Benfica, a team that opened the campaign with 7 straight shutouts, will look to frustrate their hosts on Tyneside. Mourinho’s defensive brilliance is shining through, with the Eagles shipping just 3 goals in 6 games under the experienced Portuguese, and under 2.5 goals appeals given it has landed in 4 of Benfica’s last 5 matches.

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