Juventus vs Borussia Dortmund Prediction, Odds and Picks for Today, 09/16/25

Juventus have a remarkable record when playing their first Champions League game of the campaign at home, going unbeaten in all 14 occasions that they have started in their own backyard, and they look good to make it 15 when they host Borussia Dortmund on Tuesday. The Old Lady have won all 3 Serie A games this season, including an impressive 4-3 victory over Inter Milan last weekend, and they face a BVB team that has struggled on the road in Europe.

Dortmund have lost 5 of their 6 away games against Italian teams in Europe, including a 2-1 loss against Bologna last season. Niko Kovac’s men have had a solid start to the campaign, barring a 3-3 tie with St. Pauli, but they are yet to face a team of Juventus’ quality. Igor Tudor is doing a solid job as manager of the Old Lady and should be able to mastermind a win over their German opponents in this one.

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