Brighton & Hove Albion vs Manchester United Prediction, Odds and Picks for Today, 10/25/25

Manchester United secured what has to be the best result of Ruben Amorim’s time in charge so far last weekend, as they ran out 2-1 winners at Anfield. Now, they have to back that up against a tough Brighton side in a 12:30pm ET kick-off in the Premier League on Saturday.

Albion did the league double-over United last season and are on a 5-game unbeaten run, but at the current prices, a victory for the home side looks the best angle. Amorim and United have more than their fair share of critics, but in general, their results have been positive at Old Trafford. The Red Devils only loss at home this season came against current pacesetters Arsenal in the opening round of games, and they have won all 3 since – beating Burnley, Chelsea and Sunderland.

Brighton picked up an impressive 2-1 win over Newcastle last weekend at the Amex, but their road results have been mixed. The Seagulls have lost at Everton and Bournemouth, picked up a point at bottom club Wolves, and have 1 win – albeit an eye-catching 3-1 success at Chelsea.

This match should be fairly close, but United should draw plenty of confidence from beating Liverpool. With home-pitch, they can grind out a win over Brighton.

Brighton vs Manchester United prediction: Manchester United ML (+100) at the time of publishing. Playable to -110.

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