Inter Milan vs Liverpool Prediction, Odds and Picks for Today, 12/09/25

Liverpool will try to put the controversy over Mo Salah’s future and their Premier League struggles to one side when they resume their Champions League campaign at Inter Milan on Tuesday. The defending champions are in a hole domestically after Saturday’s 3-3 tie with Leeds, and Salah’s vicious outburst will not have helped as he expressed frustration at being relegated to the bench in recent games at boss Arne Slot and the club overall.

However, an outing in Europe could bring the positivity back. It is fair to say there were plenty of good signs in the hectic draw at Elland Road before the defensive mishaps that cost the Reds a valuable three points. Liverpool’s performances and results in the competition this season have often been markedly better than in the league, with 3 wins from 5 so far, including an impressive 1-0 victory over Real Madrid at Anfield last month. The shock 4-1 slump at home to PSV Eindhoven a few weeks ago, though, was an untimely setback, and now the Reds must try to respond as they look to move back towards the top 8 in the Champions League standings.

A trip to the San Siro is a tough challenge for any team but Slot’s men won 3-1 there last season against Inter’s city rivals AC Milan in their league phase opener, and Liverpool have won on their last 4 trips to the famous stadium. Inter will likely approach the game with plenty of confidence but facing a team that is prepared to attack rather than concentrating on simply sitting in and nullifying them may also work in Liverpool’s favor.

Inter are on a 3-game winning streak, which includes Saturday’s 4-0 home demolition of Como in Serie A, and their only setback in the Champions League came on matchday 5 when they slipped to a late 2-1 defeat at Atletico Madrid. However, Liverpool look good value to claim a familiar road win at this stadium again.

Inter Milan vs Liverpool prediction: Liverpool ML (+240) available at time of publishing. Playable to +200.

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