Marseille vs Liverpool Prediction, Odds and Picks for Wednesday, 01/21/26

4 wins from 6 Champions League matches has Liverpool on the cusp of the top 8 in the 36-team standings, but there is nothing straightforward about this trip to Marseille. The Reds have pieced together a 12-game unbeaten run since suffering a humiliating 4-1 defeat at home to PSV on Matchday 5, but they have been held to draws in 4 of their last 5 outings. Premier League strugglers Burnley snatched a point at Anfield in a 1-1 tie on Saturday, with Liverpool punished for their slack finishing as Dominik Szoboszlai missed a first-half penalty and Arne Slot’s side dominated the shot count 32-7. Liverpool have now conceded in 5 of their last 7 matches, which includes at home to League One club Barnsley in the FA Cup 3rd round, and Marseille have an array of attacking talent at their disposal.

Roberto De Zerbi’s team sits 3rd in Ligue 1, 8 points behind leaders Lens, but Saturday’s 5-2 success at Angers came hot on the heels of a 9-0 thrashing of Bayeux in the Coupe de France. Prior to that, Marseille would have felt unfortunate to lose on penalties to Paris St-Germain in the French Super Cup final on neutral soil in Kuwait following a 2-2 draw, and they have plenty of former Premier League talent on show. Mason Greenwood, Pierre-Emerick Aubameyang, Angel Gomes, Pierre-Emile Hojbjerg, Matt O’Riley, Emerson and CJ Egan-Riley all now ply their trade for OM and they have excelled at the Stade Velodrome, where they have won 8 of their 12 matches this season.

Marseille have recorded home wins over Ajax and Newcastle in the Champions League and, having also triumphed 3-2 away at Union Saint-Gilloise and pushed Real Madrid close in a 2-1 defeat at the Bernabeu, they certainly have the resources required to trouble Liverpool. The Reds are still creating plenty of chances and their forward talent speaks for itself, but Slot’s side have managed only shutouts in 12 road games. All signs point to goals in this one.

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