Newcastle United vs Liverpool Prediction, Odds and Picks for Monday, 08/25/25

The distraction of Alexander Isak’s future is likely to dominate the build-up to Newcastle’s Monday matchup with champions Liverpool, and there is little doubt that the Magpies could do with the situation being resolved as quickly as possible. The effect that the Swedish striker downing tools has had on the Magpies’ dressing room is difficult to gauge as he aims for a move to Anfield before the end of the month, but it is a situation Eddie Howe needs sorted so he can recruit a replacement. With the Reds coming to town, that need is urgent as he fielded a team without a recognized centre forward at Aston Villa on Saturday and the Magpies consequently lacked a cutting edge. Anthony Gordon is not a long-term solution in the role and it does not bode well with Arne Slot’s team having already scored 4 in their opener against Bournemouth.

This matchup was a thrilling 3-3 tie last season and while the Magpies’ final 2 St. James’ Park outings featured fewer than 3 goals, over 2.5 was a winning bet in their previous 12. But it is questionable whether the home side will have enough of a goal threat in Isak’s absence to repel the champions. It seems difficult to see Newcastle matching the champions in terms of productivity and they look vulnerable to suffering a defeat.

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