Vancouver Whitecaps vs Los Angeles FC Prediction, Odds and Picks for Saturday, 11/22/25

Vancouver host LAFC at a sold-out BC Place and the Whitecaps are expected to make home advantage count in this MLS Western Conference semifinal. The Blue and White won 18 of their 34 conference matches and no team in the division scored more than the Whitecaps’ 66 regular-season goals. FC Dallas were crushed 3-0 by Vancouver at BC Place in the 2nd leg of their playoff clash and the stats from that victory will make alarming reading for LAFC. Jesper Sorensen’s men hit 22 shots, 10 corners and the Expected Goals numbers finished 3.60 to 0.38 in the Whitecaps’ favor. Vancouver will have to keep Heung-Min Son quiet, but the Whitecaps should be hard to beat at home.

Vancouver Whitecaps vs Los Angeles FC prediction: Vancouver ML (+110) available at time of publishing. Playable to -110.

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