Real Madrid vs Manchester City Prediction, Odds and Picks for Today, 12/10/25

Real Madrid have eliminated Manchester City from the Champions League in each of the last 2 seasons, and while their future in the competition is not under threat on Wednesday, defeat for Pep Guardiola’s team could leave them in a precarious position heading towards the end of 2025. However, Los Blancos have only won 2 of their last 7 games and they may fail to live up to their slight favouritism against a Citizens side heading to the Spanish capital off the back of 3 straight victories. These 3 wins have produced a massive 17 goals in total, and more goals can be expected when 2 of the world’s best strikers lock horns on Wednesday.

Kylian Mbappe and Erling Haaland have scored 45 goals for their respective clubs between them this season, but it is the Frenchman who enters this game in better form. Mbappe has scored 9 goals in 5 Champions League outings so far and has only failed to score in 2 of his last 6 games for club and country, notching an impressive 9 goals in this period. He has 7 goals in seven previous meetings with Manchester City and scored a hat-trick against them at the Bernabeu earlier this year, so should contribute to a high-scoring clash.

Real Madrid vs Manchester City prediction: Over 3.5 goals (+124) available at time of publishing. Playable to +110.

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