Wolverhampton Wanderers vs Manchester City Prediction, Odds and Picks for Today, 08/16/25

Manchester City’s quest to reclaim the Premier League title opens with a trip to Molineux to face a Wolves team in transition on Saturday. Pep Guardiola’s side are also in a bit of flux after the City boss demanded reinforcements and began dismantling the squad that won 4 titles in a row.

Jack Grealish is the latest big-name casualty of Guardiola’s pruning, although the England winger had looked to be yesterday’s man for most of last season. Ederson looks set to be the next in the firing line with James Trafford brought back to offer stiff competition for the #1 shirt.

The former champions usually kick off the campaign with 3 points and there is very little reason to suspect they will trip up at Molineux. City signed Wolves’ best player, Rayan Ait-Nouri, almost as soon as the curtain fell on a campaign that saw Wolves trail home in 16th place.

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