Real Madrid vs Marseille Prediction, Odds and Picks for Today, 09/16/25

Marseille have never beaten Real Madrid in 4 attempts and the wait looks set to go on for the French raiders this week. They head to Spain for their opening encounter in this season’s Champions League and we predict a comfortable victory for the in-form Los Blancos. Real have won all 4 matches so far and Xabi Alonso’s side are finding goals easy to come by too. The Bernabeu boys are top of La Liga with a perfect record and they have scored at least 2 goals in each of their last 3 games. Meetings with Marseille have followed a similar theme, so backing a Real Madrid to win and shut out Marseille looks the best course of action in this intriguing clash. Marseille have lost their 2 road games this season, failing to score in both, and Real should be able to continue that trend here.

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