Chicago Fire vs Orlando City SC Prediction, Odds and Picks for Today, 10/22/25

A place in the MLS playoffs is up for grabs when Chicago Fire host Orlando City, and a cagey clash is expected with so much on the line. The Fire’s last 3 games have gone over 3.5 goals but the pair’s last meeting in Chicago finished 0-0, and another low-scoring clash is expected.

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